What are the symptoms of stage 5 kidney disease? Chronic kidney disease stage
5 means that patients have become uremia stage. GFR is less than 15 and serum
creatinine is more than 707umol/L. In this stage, there are many toxins which
accumulate in the body because kidney fails. The toxins give damage to many
other organs or systems such as digestive system, nerve system, heart and so
on.
As for digestive system’s damage, patients will feel nausea, vomiting, poor
appetite, etc. As for the nerve system, patients may easy fall asleep, fatigue,
dizzy, etc. Stage 5 kidney disease can also have anemia, which is caused by the
insufficiency of EPO generation. EPO is produced in kidney. When kidney fails,
the secretion decreases, the red blood cells can not generate normally, thus
causing anemia and patients look pale on face. In turn, kidney failure leads to
many toxins in the body, which threaten the life of red blood cells, worsening
anemia.
What’s more, high blood pressure or hypertension will also take place in
stage 5 of chronic kidney disease.
About 23% to 70% patients with chronic renal glomerular nephritis will suffer
from high blood pressure with the disease developing. The more renal function
declines, the higher blood pressure will be. In addition, lesion in renal
parenchyma and renal tubules can also lead to high blood pressure such as
insufficiency of chronic pyelonephritis. Half of them can lead to high blood
pressure. High blood pressure or hypertension will in turn damage kidney. High
blood pressure makes the heart work harder and, over time, can damage blood
vessels throughout the body. If the blood vessels in the kidneys are damaged,
they may stop removing wastes and extra fluid from the body. The extra fluid in
the blood vessels may then raise blood pressure even more. It's a dangerous
cycle.
Pain in the back can also takes place, especially for those with PKD, renal
cysts and so on. Other kidney disease patients can also feel painful in back
when it is knocked.
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