Tuesday, June 4, 2013

How does Diabetes Affect Kidney Function

Once diagnosed with diabetes, patients are reminded to take care by their doctor for it may affect kidney function and develop into kidney disease some day. How does diabetes effect kidney function? We should explain it from two aspects.
On one hand, high blood glucose is the main and typical symptom of diabetes. However, long time high blood sugar can decline immunity, and lead to the disorder of immune defense. In addition, long time blood glucose can also lead to dense plasma, which makes the micro-blood vessels blocked, and further influencing the blood vessels in the whole blood system, kidney blood vessels included. With time passing by, renal insufficiency takes place and renal function is effected.
On the other hand, one complication of diabetes is high blood pressure. On the basis of cytology, Hypertensive Nephropathy is a kind of kidney disorder, the damage of which is endothelial cell because of insufficiency of blood. When patients are in hypertension or high blood pressure condition, blood pressure will not keep stable, which rises or decreases suddenly. In this case, the rising and falling blood pressure will stimulate the renal glomerular capillaries, which leads the wall of the renal glomerular to suffer from more pressure. The capillary walls suffer from brushing, which leads the lumen of renal capillary to become narrower, thus causing renal insufficiency. In this condition, the renal glomerular capillaries will be damaged, which attracts the infiltration of inflammatory cells. Long time filtration will make the structure of the cells change. Then, the renal glomerular filtration function will be damaged, thus causing kidney failure, and kidney function is effected at the same time.
From the above, we have a general view on how diabetes effects kidney function. Since having had been effected, we should take measures to treat.

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