The clinical manifestations of Lupus Nephritis has some relationship with its
pathological change. Generally speaking, the manifestation of mesangium
glomerular nephritis is relatively slight, and there is no abnormal urine, which
can appear as latent nephritis. Focal segmental proliferative nephritis can also
be called latent nephritis or chronic nephritis. Few of them can exist as
Nephrotic Syndrome. Diffuse prolilferative nephritis can also manifest as
Nephrotic Syndrome, which accounts for about 75%.
At present, according to the type classification of WHO, it is believed that
it can not supply enough judgement for the prognosis and treatment. So later,
the activity index is created.
Evaluating the activity index of Lupus Nephritis is a convenient method which
can judge how serious the condition is and the activity degree of Lupus
Nephritis. In addition, it is also a good evidence which can instruct the draft
of clinical treatment. On the basis of experts Ye Zhigao in China, we divide
Lupus Nephritis into three levels.
1. If the point is 7 to 10, it indicates that patients are in active activity
period.
2. If the point is 3 to 6, it indicates that patients are in moderate
activity period.
3. If the point is 1to 3, it indicates that patients are in mild activity
period.
4. If the point is less than 1 point, it indicates that the condition is
stable, or patients are in quiet stage.
According to the above mentioned, we can use different dosage of hormone,
cyclophosphamide, and other medicine such as Chinese medicine to treat it. In
western countries, more and more patients are seeking a more effective method
which can stop their suffering considering the side effects hormones cause.
Diminishing the above side effects and inheriting the advantages of
traditional Chinese medicine, Immunotherapy includes both Chinese medicine, stem
cells and some western medicine. It has little side effect and can also focus on
the pathological mechanism: immune problem. Further speaking, it can be divided
into 6 steps, which includes scientific diagnosis, immune inhibition, immune
tolerance, immune adjustment, immune protection and immune clearance.
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