If you are diagnosed with Diabetes for several years, you should be alert to
high creatinine level by blood test regularly since it may be connected with
kidney damage.
Creatinine is the end products of creatine in muscle and normally it is
excreted by kidneys. However, if your kidneys fails to work, a lot of wastes
will stay in body, leading to high creatinine. For strong compensatory capacity
of kidneys, initially, the creatinine level does not increase at all. It rises
until more than 50% renal function has been lost. So, testing blood is a
necessity, especially on the level of creatinine, blood urea nitrogen(BUN) and
urea acid, etc.
How does Diabetes damage kidney and lead to diabetic kidney disease?
The occurrence of Diabetic Nephropathy is closely connected with high blood
sugar or high blood glucose in diabetic patients. If the blood sugar or blood
glucose is not controlled well, it will accelerate Diabetic Nephropathy. Well
controlled blood sugar can also delay the development of Diabetic Nephropathy.
If not controlled well, there will be increased proliferation of renal mesangial
cells and increased ECM, thus causing thicker renal glomerular basilar membrane.
In clinic, protein in urine and so on will come into being.
How to prevent diabetes developing into diabetic kidney disease with high
creatinine ?
1. Uncontrolled blood glucose level is the principle culprit of Diabetes
Kidney Disease. You should monitor your blood glucose level regularly and take
test four times a day.
2. Controlling blood pressure is a vital part in slowing down Diabetes Kidney
Disease progression. You should keep the blood pressure within 130/80 mmHg by
taking ACEI or ARB which can lower blood pressure and also has certain effect in
preserving renal function.
3. Too much meat consumption can cause more production of creatine,
especially lean meat. So keep a low protein intake.
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