Thursday, June 20, 2013

Diabetics Should Be Alter to High Creatinine

If you are diagnosed with Diabetes for several years, you should be alert to high creatinine level by blood test regularly since it may be connected with kidney damage.
Creatinine is the end products of creatine in muscle and normally it is excreted by kidneys. However, if your kidneys fails to work, a lot of wastes will stay in body, leading to high creatinine. For strong compensatory capacity of kidneys, initially, the creatinine level does not increase at all. It rises until more than 50% renal function has been lost. So, testing blood is a necessity, especially on the level of creatinine, blood urea nitrogen(BUN) and urea acid, etc.
How does Diabetes damage kidney and lead to diabetic kidney disease?
The occurrence of Diabetic Nephropathy is closely connected with high blood sugar or high blood glucose in diabetic patients. If the blood sugar or blood glucose is not controlled well, it will accelerate Diabetic Nephropathy. Well controlled blood sugar can also delay the development of Diabetic Nephropathy. If not controlled well, there will be increased proliferation of renal mesangial cells and increased ECM, thus causing thicker renal glomerular basilar membrane. In clinic, protein in urine and so on will come into being.
How to prevent diabetes developing into diabetic kidney disease with high creatinine ?
1. Uncontrolled blood glucose level is the principle culprit of Diabetes Kidney Disease. You should monitor your blood glucose level regularly and take test four times a day.
2. Controlling blood pressure is a vital part in slowing down Diabetes Kidney Disease progression. You should keep the blood pressure within 130/80 mmHg by taking ACEI or ARB which can lower blood pressure and also has certain effect in preserving renal function.
3. Too much meat consumption can cause more production of creatine, especially lean meat. So keep a low protein intake.

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