How to Decrease Protein in Urine?

How to decrease protein in urine? This is a question which is put forward by chronic kidney disease patients who have protein in urine and the urine which contains a large amount of protein is called proteinuria. Generally, in a normal condition, there is a little protein in urine, the amount of which is about 40mg to 80mg. The maximum is 150mg. Youngsters have higher level. If there is more than 150mg per day, we can call it proteinuria.
Proteinuria can be caused by many factors such as long time standing, taking exercise, and so on, all of which are just for the time being and can disappear some time later. However, if the protein in urine lasts for more than three months, which is often accompanied by hematuria, and sometimes with decreased glomerular filtration rate, which is short for GFR.
Long time protein in urine will of course lead to a series of damage. Firstly, if there is more protein in urine, there consequently must be less protein in the plasma, which is called hypoproteinemia in clinic. In turn, hypoproteinemia will lead to edema or swelling in the body. So once there appears protein in urine, especially when it lasts for a long time, chronic kidney disease patients will become anxious and seek for an effective treatment.
To decrease the protein in urine has become the focus of the chronic kidney disease patients. How to achieve it? To solve the problem, we should firstly figure out why and where protein leaks out into urine. Protein leaks out from the filtration membrane of kidney, the structure of which is just like a griddle, in which, there are many pores. The diameter of the pores is limited, so in normal condition, there are only small molecules which can pass through such as creatinine. However, when the kidney suffers from damage, the filtration membrane will also be damaged, the diameter of whose pores will also change. In this case, some bigger molecules such as protein will leak out, thus causing protein in urine.
Since that we have figured out the reason why there appears protein in urine, we can think over the solutions to decrease the protein in urine.
Chinese Medicine can make it. It is abstracted from traditional Chinese medicine, which is more convenient and the ratio of use is also more effective in contrast to the traditional Chinese medicine. It is from Chinese herbs mostly, so it contains nutritious and active materials which can give nutrition to the damaged filtration membrane, thus repairing it. After that, the pores’ diameter turns normal, thus stopping the leaking out of protein in urine.

How to Reduce Serum Creatinine

How to reduce serum creatinine? As we mentioned in the above, creatinine can both exist in serum and urine. Creatinine in serum is called serum creatinine, which is used to be a very important diagnosis to judge the renal function. Generally, the total amount of creatinine is stable in normal condition. If there is more in urine, there will be less in serum. In turn, if there is less in urine, there will be more in serum. If there is more creatinine in urine, it indicates that kidney is damaged and kidney function is declined accordingly for creatinine can pass through pores of renal glomerular filtration rate.
How to reduce serum creatinine? In clinic, especially in western countries, when chronic kidney disease patients have symptoms such as proteinuria, they are usually told to take western medicines, most of which just focuses on diminishing them fast, however, the effect of them are for the time being.
So how to reduce serum creatinine fundamentally has become a hot topic today.
In China, we have Chinese Medicine. Firstly, in Chinese Medicine, there are much nutritious materials which can supply nutrition to the kidney and improve the insufficiency of blood and oxygen in the kidney. Secondly, when a good and clean inner environment is created, the nutritious materials will play roles in repairing intrinsic cells and damaged renal glomerular basilar membrane, thus stopping the further damage to the kidney. Thirdly, Chinese Medicine can also clear away the immune complex which deposit into the kidney.
Besides these, patients with chronic kidney disease should also pay attention to the other aspects so as to assure the decrease of serum creatinine during the treatment. The detailed explanations are as follows:
First of all, prevent themselves from catching a cold. Catching a cold can worsen kidney disease sharply. In this course, catching a cold or getting an infection can lead to more deposition of immune complex. A cold can increase creatinine in serum a lot.
Secondly, pay more attention to the diet as well. Coca cola, which is very popular in many countries in the world, should also be forbidden for chronic kidney disease.
The above mentioned are about how to reduce serum creatinine.

Primary Glomerularnephritis

Manifestations:
Primary Glomerularnephritis is a group of renal glomerular disease, the clinical manifestations of which are proteinuria, hematuria, edema, high blood pressure, and so on. Different patients have different degree of manifestations. For most of them, edema or swelling is their first symptom. Early in the morning, slight patients can find moderate swelling in the eyelids and face. In the afternoon, there is slight edema in lower limbs. After a short time rest, the edema can disappear. For some of them, increased blood pressure is the first symptom and then they are diagnosed with chronic Primary Glomerularnephritis. If not controlled well, Primary Glomerularnephritis may develop into renal insufficiency and even renal failure. Patients will have anemia, heart failure, and so on, which is mainly due to the damaged renal parenchyma, thus causing decreased production of red blood cells and malnutrition.
The types:
In clinic, Primary Glomerularnephritis can be divided into four kinds: acute renal glomerular nephritis, progressive renal glomerular nephritis, chronic nephritis, and latent renal glomerular nephritis. According to pathological damage, it can also be divided into the following three type, the classification of which is more common and acceptable in clinic.
1. MsPGN, the full name of which is mesangial proliferative glomerulonephtitis. It is found in youngsters in most of time, and men are more than in women. The clinical manifestations of which are continuous microscopic hematuria, recurrent hematuria, and the disease usually lasts for a long time. About half of them have been infected before. 70% of them have gross hematuria. With the disease developing, high blood pressure and renal failure will appear.
2. Chronic diffuse renal glomerulonephtitis or focal segmental renal glomerulonephtitis, which is from acute renal glomerulonephtitis that can not recover for a long time.
3. Membranous Glomerulonephritis, 80% of which show symptoms of nephrotic syndrome. Nephrotic Syndrome refers to a group of renal glomerular disease. When the protein in urine is more than 3.5g/24h and the symptoms of hypoproteinemia occur, you can be diagnosed as Nephrotic Syndrome. Other common symptoms also include severe edema and hyperlipemia. Some also show symptoms of chronic nephritis.

What Is the Result of Bilateral Grade 3 Renal Parenchymal Disease

I am suffering from bilateral grade 3 renal parenchymal disease. Now my creatinine is 278umol/L. I have no obvious symptoms but the report shows that the protein in urine is 2+. What is the result of my condition.
Generally, the renal parenchymal disease means that the damage takes place in renal glomerulus, which play important function in the kidney such as filtration toxins such as creatinine, blood urea nitrogen, etc. It is actually more serious that the damage in the renal mesengial area, in which, renal tubules are damaged in most of time.
As you describe, there is 2+ protein in urine, it means that the renal glomerulus are damaged, for in renal glomerulus, there is filtration membrane, through which, protein, red blood cells, white blood cells come out of the body into urine.
If we do not take effective measures, the pore of the renal glomerular membrane will become bigger with the protein leaking out every day, and there will be more protein leaking out. In clinic, the protein leaking out can be as much as 4+. If proteinuria lasts for a long time, the blood will have low protein, which is called hypoproteinemia. If hypoproteinemia lasts for a long time, the osmotic pressure in blood will change, which leads to edema or swelling or dropsy in clinic. Protein in urine, which is as much as more than 3.5g in 24 hours, low protein in blood, edema, and high fat, all of these will form nephrotic syndrome.
So please be aware of your current condition and choose a better therapy which not only has no side effect but also can treat it fundamentally.
On the basis of this, in our Hospital, we have Chinese Medicine, which can repair the damaged renal glomerular membrane by extending blood vessels, dissolving the blood stasis and then supplying nutrition to the kidney.

Life Expectancy of Stage 5 Chronic Kidney Disease

Life expectancy of stage 5 chronic kidney disease is concerned about by many people who are in this stage. In stage 5, GFR falls down to 15% and the creatinine is more than 707. In China and other countries, people nearly all come to dialysis period. The symptoms includes itch, nausea, loss of appetite, tiredness, pins and needles in the hands or feet and, at a late stage, chest pain due to pericarditis, which is inflammation of the lining around the outside of the heart. Bleeding and bruising become more prominent. Patients are often prone to infection and develop fluid retention with ankle swelling and shortness of breath.
In stage 5 of chronic kidney disease, patients under dialysis for a long time will ask the life expectancy for they have no confidence on dialysis. Indeed, dialysis can help discharge excessive water, toxins in the body, which however, has many disadvantage. Firstly, there must be damaged cells in the kidney, which dialysis can not repair. Secondly, there are also necrotic cells in the kidney, which dialysis can not differentiate. What’s worse, kidney disease is developing, it can not stop. So to increase the life expectancy of chronic kidney disease patients, we should find out a new therapy and stem cell therapy is considered till now the best one to turn the table.
Stem cells are biological cells found in all multicellular organisms, that can divide (through mitosis) and differentiate into diverse specialized cell types and can self-renew to produce more stem cells. It can be used to treat many kinds of diseases such as blood disease, diabetes and kidney diseases. The application ways of stem cell can be divided into two kinds: injection via vein and transplantation. The latter one needs stage 5 chronic kidney disease patients to take in medicine to prevent the rejection after transplantation.
In our Hospital, we mainly use the former one, which means that patients inject stem cell, which is convenient and safer. After this, the life expectancy of chronic kidney disease will be prolonged.

When Diabetes Develop into Diabetic Kidney Disease

When does diabetes develop into diabetic kidney disease?How diabetes affect kidney? The most typical characteristic of diabetes is that there is high blood sugar, which firstly influences all the blood vessels especially the micro-blood vessels, which can influence the micro-blood vessels in kidney as well. If it lasts for a long time, the kidneys can't filter out toxins as well if they're damaged.
Although kidney at the beginning has increased filtrating rate for a while, the presence of glucose increases the amount of filtrates passing through the functional units of the kidneys, which lead to more protein being filtered across the glomerular membranes. This is followed by the appearance of small amounts of protein in the urine. In turn, the protein which filtered out of body damages the membranes leading to increasing losses of protein in the urine and more damage to the kidneys.
On the other hand, the increased tendency to atherosclerosis in diabetes also lead to damage in kidney. There is an increased level of blood fats with deposits in the walls of the blood vessels. Where this affects the blood supply to the kidneys, the diminished blood flow can also damage the kidneys.
The above mentioned tells us when diabetes develops into diabetic kidney disease or how diabetes affect kidney.

Long-time diabetes can cause various complications and one of them is kidney disease. The pathological mechanism goes as follows:
When our bodies metabolize the protein we take in, the process creates waste products. In the kidneys, millions of tiny blood vessels (capillaries) with even tinier holes in them act as filters. As blood flows through the blood vessels, small molecules such as waste products squeeze through the holes. These waste products become part of the urine. Useful substances, such as protein and red blood cells, are too big to pass through the holes in the filter and stay in the blood.
Diabetes can damage this system. High levels of blood sugar make the kidneys filter too much blood. All this extra work is hard on the filters. After many years, they start to leak and useful protein is lost in the urine. Having small amounts of protein in the urine is called microalbuminuria.
When kidney disease is diagnosed in early stage, (during microalbuminuria), several treatments may keep kidney disease from getting worse. Having larger amounts of protein in the urine is called macroalbuminuria. When kidney disease is caught later (during macroalbuminuria), end-stage renal disease, or ESRD, usually follows. This is how diabetes develops into kidney disease even kidney failure.
During diabetic nephropathy, the main damaged part of kidney is glomerular basilar membrane, which indicates us that we should repair the damaged renal glomerular membrane. This is the critical and core therapy which can stop diabetes developing into renal failure.
On the basis of this, our Hospital created Chinese Medicine, which is abstracted from natural herbs and can promote the blood circulation, improve the micro-blood circulation, relieve the insufficiency of blood and oxygen in the kidney blood vessels, thus creating a favorable for the repair of the damaged cells in the kidney. After this, the active materials will take effect in supplying nutrition for the damaged cells, thus reviving kidney function and preventing diabetes from kidney disease and kidney failure.

Glomerulonephritis Hematuria and Treatment

What is glomerulonephritis hematuria? Hematuria means that there are red blood cells in urine, which can be divided into gross hematuria and microscopic hematuria. Gross hematuria means that with our naked eyes, we can see the urine looks like water where flesh is washed and microscopic hematuria means that with the help of microscopy, we can see more than 3 red blood cells. Why do we say glomerulonephritis hematuria? It is because red blood cells both in gross hematuria and in microscopic hematuria are due to the damage in glomeruli.
Glomeruli are important elements in the renal units or nephrons, which plays an important role. In each glomeruli, there is filtration barrier which includes basilar membrane. And in every basilar membrane, we can see pores, through which, small molecules pass such as creatinine, urea acid and so on. In normal condition, the diameter in basilar membrane is relatively small, through which, red blood cells can not pass. However, when kidney is damaged due to excessive immune response and so on, the intrinsic cells will also be damaged and accordingly, the diameter of pores will become bigger. And in this case, some bigger molecules such as red blood cells will leak out, thus forming hematuria. Strictly speaking, gross hematuria is more serious than microscopic hematuria, as we can get a conclusion from their name.
Many kinds of kidney diseases belong to glomerulonephritis such as lupus nephritis and purpura nephritis. How to treat glomerulonephritis then especially those with hematuria?
In our Hospital, we have immune therapy to treat glomerulonephritis which includes many therapies such as chinese medicine, stem cell transplant and some western medicine such as glucocorticoid and so on. And the whole immune therapy can be generally divided into six steps which go as follows: scientific treatment, brand new medicine and immune inhibition, immune tolerance, immune adjustment, immune protection and immune clearance. As we know, lupus nephritis and purpura nephritis and so on are caused by immune disorder. So we mainly adopt immunotherapy, which is more advanced than that in western medicine because the immunotherapy in our Hospital is the combination of western medicine and Chinese medicine. Take Chinese Medicine for example. It is abstracted from traditional Chinese medicine and is more effective and convenient than traditional Chinese medicine. It is especially good at the repairing of damaged intrinsic cells including the pores in basilar membrane as well.

How to Treat Nephritis with Stem Cell and Chinese Herbs

When it comes to Nephritis, we mainly refer to chronic renal glomerular nephritis, which accounts for more than half of chronic kidney disease including lupus nephritis, purpura nephritis, etc. As its name implies, nephritis means a condition in which there is inflammation. The pathological bacteria or virus invades, the immune system will protect. However, when immune system is out of order, the combination of antigen and antibody which is also called immune complex will deposit onto the organs and will not be cleared away into urine. The immune complex will also deposit into kidney. As we know, kidney will not allow abnormal things to stay in the kidney so inflammation reaction takes place, which will damage the healthy cells and tissues in the kidney. In most of the time, inflammation reaction takes place in renal glomeruli, so we call it renal glomerular nephritis.
When renal glomerular nephritis takes place in the early stage, the symptoms are not obvious. For children, in the urinalysis examinations, there appears protein in urine and red blood cells in urine, which worsens after strenuous exercise or infection. Generally, with children growing, there will be more and more protein in urine. What’s worse, some can have severe protein in urine. They seldom have increased blood pressure and usually in the end stage, blood pressure begins to increase. Renal glomerular nephritis usually develops slowly, and male patients usually have worse condition.
Generally, firstly, we should block the immune inflammation reaction so as to stop the damaged and then we should try to regulate the immune system so as to increase the immune ability. In this case, the body itself can clear away the immune complex and treat renal glomerular nephritis from root.
In our Hospital, we have immunotherapy which is a systematic therapy of both Chinese herbs and western medicine as well as cell therapy. It can regulate the immune system thus treating nephritis from root.

Can a Lady with Nephrotic Syndrome Conceive?

Can a lady with Nephrotic Syndrome conceive? Nephrotic Syndrome is a chronic kidney disease, which is not very easy to cure and the recurrence rate is high. As for young ladies, they also consider one more question: can they conceive? Firstly, we would like to introduce the harm that conceiving will bring.
1. Renal insufficiency caused by low albumin in the plasma, which leads to the low growth of fetus or baby who is born in advance.
2. Conceiving or pregnancy can give more burden to the kidney, for there are two persons in one body. In this case, mother will eat more, drink more. However, there are only two kidneys.
3. Since mother is suffering from Nephrotic Syndrome, she will take in some western medicine such as hormone, hypotensor, and so on, which will do great harm to the fetus.
Considering these, we can get a conclusion that ladies with Nephrotic Syndrome had better not have a baby. So there will come another question: when they can have a baby. Please do not worry. Experts in kidney disease field give you the following advice.
1. After all the indexes turn normal such as protein in urine, red blood cells in urine, and so on, ladies can consider having a baby.
2. After patients stopped using medicine for at least half a year, they can consider being pregnant for there will be medicine in mother’s body which may do harm to little fetus’ health.
3. Ladies who have no high blood pressure and infection in urinary tract can consider conceiving.
4. After renal biopsy, patients find out that there is only slight pathological damage in the kidney.
Last but not least, when ladies with Nephrotic Syndrome want to have a baby, they had better ask the doctors for advice firstly.
Last but not least, ladies with Nephrotic Syndrome are also concerned about the treatment of it. Considering the side effects of some medicine and the harm it may bring to the fetus in the future, ladies with Nephrotic Syndrome are suggested to use Chinese Medicine, the medicine of which is abstracted from traditional Chinese medicine, which is quite different from western medicine for there happens a series of chemical reaction in the body. For more information about Chinese Medicine, please consult us on line or email us.

What Is Massive Edema of Nephrotic Syndrome Caused by?

Edema or swelling, is no doubt a very common symptom for patients with Nephrotic Syndrome, which is followed by proteinuria, low fat in blood.
Renal edema usually occurs in the area where the cell tissue is loose and soft. Generally, In the morning when patients with Nephrotic Syndrome get up, edema in eyelids is more serious. Till at noon and in the afternoon, edema in face generally will become more serious, which shows pitting if pressed with a finger and will not spring. However, if there is massive edema or swelling, patients will become anxious and want to treat it at once.
How to treat it? Firstly, we should figure out why edema or swelling comes into being. Renal edema refers to the phenomenon that the discharge of water is blocked, which leads to the retention of water in the body for one of kidney’s function is to filtrate and discharge it. According to the latest cytology, edema is due to the process of renal fibrosis, which leads to the damage of renal intrinsic cells and influence the normal filtration function. Consequently, a large amount of protein in urine appears, which leads to hypoproteinemia. So as for the treatment of edema, we should focus on the repair of damaged renal glomeruli.
In our Hospital, we have had Chinese Medicine, which can repair the damaged intrinsic cells, thus diminishing the massive edema eventually.

Why does Children Nephrotic Syndrome Recur time and again

Children Nephrotic Syndrome recurs time and again, which leads parents to feel headache. The reasons why　Children Nephrotic Syndrome recurs time and again are as follows:
Infection
In many cases, the recurrence of Children Nephrotic Syndrome is connected with infection such as catching a cold (flu) which leads to the respiratory tract infection. Once some Children with Nephrotic Syndrome catch a cold or get a flu, the protein in urine will turn positive and sometimes, edema or swelling may occur at the same time. Sometimes, protein in urine disappears after the cold is over, but in most cases, protein in urine will not stop unless more hormones are injected.
Long time use of a large amount of prednisone. It can lead to the shrink ofadrenal cortex. After medicine is stopped, hormone will not secrete. In this case, Children Nephrotic Syndrome may recur easily.
Not scientific treatment
In many cases, the treatment course is too short. Some parents do not follow what doctor said and stop the medicine on their own or change medicine, or reduce the amount of medicine, all of which can lead to recurrence of Children Nephrotic Syndrome.
The gene factor
In the recent 15 years, kidney disease experts all over the world have researched the relationship between the recurrence of Children Nephrotic Syndrome and the antigenicity of white blood cells.
How to prevent children from recurrence of Nephrotic Syndrome? Firstly, avoid getting infection. Try not to be too tired.
Secondly, be aware of the food which children take in. Do not have those such as fried chicken, chocolate, instant noodles with pepper, and so on.
Thirdly, stop medicine such as hormone and immunosuppressive agent and try another new therapy.
The latest treatment method for Children Nephrotic Syndrome
In our hospital, we have immunotherapy, which is the combination of western medicine and traditional Chinese medicine and can be divided into six steps: scientific diagnosis, immune inhibition with brand new medicine, immune tolerance, immune adjustment, immune protection and immune clearance.

Therapies to Treat Nephrotic Syndrome

Actually, most of the patients who are suffering from Nephrotic Syndrome, feel puzzled, why the Nephrotic Syndrome relapses again and again and so on. Obviously, the urine protein has turned negative, and urine blood disappeared after taking a period of a medicine. But, slight cold or infection or improper diets will make the disease relapse easily. Actually, the patients have entered a wrong region of treatment and in this article, we will recommend you a new therapy to treat nephrotic syndrome.
At present, the traditional treatment for Nephrotic Syndrome is adrenocortical hormone, such as prednisone, hexadecadrol, etc. Nephrotic Syndrome needs large dosage of medicine to treat. Hormone treatment has the advantage of inhibiting immune response, and stopping urine protein and occult blood symptomatically. It can not repair the renal pathological damage.
Although, urine protein and occult blood will turn to negative shortly, it is temporary actually. The disease can be induced easily by cold, tire, infection, or improper reducing medicine dosage. Moreover, the pathological damage will be worsened by each relapse, resulting in protracted disease course. Hormone treatment is also a very important cause for the relapse of Nephrotic Syndrome.
Hormone as well as other immunosuppressants and cytotoxic medicines are all targeted at the symptoms, but they can not repair the damaged kidney. Thus, if people want to treat Nephrotic Syndrome fundamentally, they must adopt the combined therapy of Chinese and Western medicine.
By this therapy, Western medicine will ease the symptoms which can solve the problems of low effect of Chinese medicine and damaged renal tissues caused by long-term application of Chinese medicine. And once the Chinese Medicine enters the lesions, the active substances in the Chinese medicine can dilate systemic vessels of all levels, provide blood and oxygen for damaged cells through increasing blood perfusion so as to fundamentally ease the renal state of ischemia and hypoxia and reduce the further impairment of renal cells.
In addition, stem cells have been applied into kidney disease treatment in recent years. Stem cells have the characters of unlimited proliferation, multi-direction differentiation, support hematopoiesis, immune regulation, self-replication etc, which can be used as the ‘seed cells’ to repair the damaged tissues and organs. In recent years, clinical research has proved that stem cells can differentiate into renal inherent cells and renal parenchyma cells etc, and then repair and rebuild the renal function. Chinese Medicine combined with Stem Cells Transplant has a therapeutic effect for treating Kidney Disease.

Is Coconut Water Safe for Kidney FSGS Patients

In FSGS stage, patients with chronic kidney disease are suggested to have more fruit which contains rich vitamin and can help them recover. However, not all fruits are suitable. For example, coconut is a common fruit in tropic area. So people who are dwelling there have chance to have coconut. FSGS patients also want to know whether it is suitable for them.
In children and some adults, FSGS presents as a nephrotic syndrome, which is characterized by edema (associated with weight gain), hypoalbuminemia (low serum albumin, a protein in the blood), hyperlipidemia and hypertension (high blood pressure). In adults it may also present as kidney failure and proteinuria, without a full-blown nephrotic syndrome.
So from the above, we can get a conclusion that FSGS patients are in kidney failure stage and there has been protein leaking out due to the damaged kidney function. At this time, if patients take in more protein, it will give more burden to the kidney. As a matter of fact, coconut contains rich protein, which does not do harm to their recovery. Besides, coconut water also contains much potassium, which should also be forbidden. For in renal failure stage, most patients are in electrolyte disorder and the level of potassium is higher than that of normal range.
Besides coconut water, FSGS patients should also avoid bananas. Bananas contain a large amount of sodium, which can also increase the burden of the kidney if it is taken in too much. In addition, too much intake of bananas can also worsen edema, blood pressure. Diabetic patients also should take in less of them for bananas contain much sugar as well.
If patients with FSGS have edema at the same time, they should also limit the intake of watermelon, pears, pineapples and so on. If patients with FSGS have anemia at the same time, they should have few oranges, which can combine with iron easily and worsen anemia. If the potassium in the patients with FSGS is high, they should also limit the intake of nut, date, shaddock, and so on for all of them contains much potassium in it.
The above mentioned are about whether patients with FSGS should have coconut water and other fruit they should limit. We sincerely hope it can benefit you and for more information, please consult us on line or email us.

The Best Treatment of FSGS in 2013

FSGS is short for Focal segmental glomerulosclerosis (FSGS),which is a cause of nephrotic syndrome in children and adolescents, as well as an important cause of kidney failure in adults. In FSGS stage, the kidney disorder is relatively serious compared with the minimal change and so on for there are damaged and even sclerotic cells in the kidney. Symptoms such as proteinuria, hematuria, high blood pressure(hypertension)will appear. The GFR (glomerular filtration rate) decreases, which indicates that there is less blood flow in the kidney. So FSGS patients are in a critical stage.
Traditional treatments for FSGS are such as
1. Aldosterone antagonist to decrease proteinuria and thus offer a degree of reno-protection
2. Angiotensin II receptor antagonist
3. ACE inhibitor
4. Corticosteroids, such as prednisone – based on the clinical judgment of physician
5. Cytotoxics, such as cyclophosphamide may be used to induce remission in patients presenting with FSGS refractory to corticosteroids, or in patients who do not tolerate steroids.
However, as we all know, all of the above mentioned therapies have side effect as well as can only diminish the symptoms.
Considering the side effects they cause, FSGS patients are seeking for the best treatment. Chinese Medicine and stem cell can treat it, which can also stop recurrence and has no side effects.
Chinese Medicine can promote blood circulation, extend all levels of arteries, improve the micro-circulation as follows:
1. Extend renal arteries and digestive arteries, improve micro-circulation, increase the effective blood perfusion volume of the whole body.
2. Improve the partial barrier of microcirculation, increase the supply of oxygen and strengthen the metabolism.
3. Relieve the disorder of inner environment which is caused by the insufficiency of oxygen.
4. Relieve the symptoms which are caused by toxic. Discharge immune complex. In addition, the active materials in Chinese Medicine can activate a series of degradative enzyme, degrade the matrix and immune complex, thus blocking the chain which can deteriorate the fibrosis. Lastly, the herbs in it can repair the damaged cells in the kidney.
How stem cell takes effect?
As we mentioned in the above, there are sclerotic cells in the kidney. Stem Cell is the latest and effective treatment for FSGS. Stem cells are initial cells with strong self-renewing and multi-differentiation abilities. They are infused into human body through intravenous injection, and then stem cells will transfer into the kidney lesions by auto-homing function. They can adjust the immune disorder by repairing the damaged glomeruli and by generating into new renal intrinsic cells to replace the scarred ones. The combination of stem cell and Chinese Medicine can make a perfect treatment for FSGS.

How to Treat FSGS in our Hospital?

FSGS is a kind of autoimmune disease mediated by immune cells. The infiltrating T cells in the glomeruli attack the kidney inherent cells directly or damage the epithelial cells by releasing vascular permeability factors.
For FSGS, the immune complex mainly consists of IgG and C3. This is on the basis of exact diagnosis. Only if we remove the immune complex deposited in the kidneys, can the disease be fundamentally cured. Otherwise, whenever we stop the medicine, the immune reaction will start again and the disease will relapse. In this step, Chinese medicine is necessary for promoting blood circulation and removing blood stasis.
Chinese Medicine is a proper treatment, which can clear away IgG and C3,etc. The Chinese medicine is micronized into one thousandths of its original size. With the action of the microwave, the medicine can arrive directly at the renal lesions through skin and channels on the back. At the same time, Chinese medicine for nourishing qi and blood has to be used to strengthen immunity. Then we have to repair the remaining inherent cells and the damaged cells so as to recover its function.
Why is it so amazing?
(1) Chinese Medicine is abstracted from Chinese herbs, without any side effect.
(2) With the help of penetrant and osmosis devices, effective Chinese Medicine is penetrated into renal lesion by external application. (As you know, any oral taking medicines will affect kidney more or less).
(3) The therapeutic mechanism of this therapy is to block the process of renal fibrosis, dilate blood vessels, promote the micro-blood circulation, repair the damaged renal intrinsic cells, and remove the stasis in channels. At the same time, Chinese Medicine has the effect like anti-inflammation, anti-coagulation, preventing blood viscosity and degrading extracellular matrixes. Last but not least, we can also use stem cell. As we know, in FSGS stage, there are necrotic or sclerosis renal nephrons.
Stem Cells can differentiate into various kinds of renal cells which the kidney need, and then the new born cells can replace the necrotic cells, thus achieving the purpose of rebuilding the renal structure and treating FSGS fundamentally.

Treat Diabetes with Stem Cell Therapy Effectively in Our Hospital

How to treat diabetes with stem cells? Diabetes is a disease in which your blood glucose or sugar levels are too high. Glucose comes from the foods you eat. Insulin is a hormone that helps the glucose get into your cells to give them energy. With type 1 diabetes, your body does not make insulin. With type 2 diabetes, the more common type, your body does not make or use insulin well. Without enough insulin, the glucose stays in your blood. People with diabetes want to get off insulin injections and other medicines to lower blood sugar or blood glucose, so they consider stem cells. On the basis of this, we use stem cell therapy which is combined with other therapies in our Hospital.
For Diabetes, we mainly adopted a systematic immunotherapy consists of immunoadsorption technique, herbal osmotherapy and stem cell therapy to rectify the disorder in insulin secretion and acceptance system. For type two diabetes, the pancreas islet secretes insulin, but certain amount of these insulins are of faulty structure. In addition, the whole body immune system in type 2 diabete patient is in disorder, which makes cells insensitive to insulin stimulation. These two factors contribute to inefficient sugar utilization within body and sugar retention within body. Diabetes itself is not fatal, but the danger exists in various complications that might be caused by high sugar level. For example, inefficient sugar utilization leads to lipid dissolving, and lipid deposition on blood vessels can easily give rise to thrombus. Thrombus in the brain, heart and kidneys are the main causation of diabetic patient's death.
Based on the specific pathology of diabetes, the immunotherapy is adopted to rectify this disorder in insulin secretion and acceptance system. First, herbal therapies are adopted to promote whole body blood circulation and degrade blood stasis to prevent the formation of thrombus. This therapy also enhances self-recuperating ability of immune system. Stem cell therapies focus on restructuring the pancreas islet and enhance pancreas islet secreting normal structure insulin. Stem cell therapy, together with T-reg cell therapy, also enhance cells' sensitivity to insulin to promote insulin utilization within body. Clinical practices has shown a satisfying therapeutic effect, and especially for early stage Diabetic patients.
Over time, having too much glucose in your blood can cause serious problems. It can damage your eyes, kidneys, and nerves. When diabetes influences kidney, it is called diabetic kidney disease or diabetic kidney disease. So besides weight control, sticking to your meal plan, you should also seize time to treat.

Where Is There Protein in Urine for Diabetes?

Where is there protein in urine for diabetes? It indicates that there is damage in the kidney. Damage in kidney which is caused by long time diabetes is called diabetic kidney disease or diabetic nephropathy. In the early stage of diabetic nephropathy in particular, there will be protein leaking out of the body into urine. The main protein is albumin. After kidney is damaged, the permeability of capillary blood vessels in the kidney is also damaged, thus causing the leaking out of albumin.
Why is there mainly albumin? High blood sugar condition can promote the reabsorption of sodium, which can increase the content of liquid out of the cells. ANF can make the prerenal tubules blood vessels expand and the shrink of the post-blood vessels, thus causing the ultrafiltration and the ultraperfusion. The final metabolism of sugar can also lead to increased renal glomerular basilar membrane and the ECM, which can damage the renal structure and renal function.
Besides, the leaking out of urine is also connected with the controlling of the blood sugar. If the blood sugar is controlled well, diabetic kidney disease will not take place. If we take in more protein, it will also give more burden to the filtration of the kidney, thus accelerating the sclerosis of the renal glomerular capillary blood vessels.
So if we want to control or prevent the leaking out of the protein in urine, we should firstly treat diabetes and control the level of blood sugar or glucose. Besides diet, exercise, and so on, treatment is also critical, which can even help patients get off insulin injection. Stem cell therapy is considered to be the priority of the treatment which can help adjust the insulin secretion by repairing beta cell.

Diabetes and Stage 3 Chronic Kidney Disease

Each kidney is made of hundreds of thousands of small units called nephrons. These structures filter your blood and help remove wastes from your body. In people with diabetes, the nephrons thicken and slowly become scarred over time. The kidneys begin to leak and protein (albumin) passes into the urine. When the GFR declines to 30~59 ml/min (serum creatinine is 186-442umol/l), it indicates that diabetes has developed into diabetic kidney disease stage 3. It is a critical stage and patients should seize the time to treat. If the treatment is effective, the condition can be reversed.
How diabetes develops into stage 3 chronic kidney disease?
The exact cause is unknown. Poor control of blood sugar is thought to lead to kidney damage. If you also have high blood pressure, kidney damage is even more likely.
In some cases, family history may also play a role. Not everyone with diabetes develops this kidney problem.
People with diabetes who smoke, and those with type 1 diabetes that started before age 20 have a higher risk for kidney problems.
Symptoms of diabetic kidney disease stage 3 are as follows:
Often, there are no symptoms as the kidney damage starts and slowly gets worse. Kidney damage can begin 5 to 10 years before symptoms start.
People who have more severe kidney disease may have a poor appetite, feel tired most of the time, and have a general ill feeling.
Headache, nausea and vomiting,swelling of the legs, and many other symptoms may also occur.
Treatment for diabetic kidney disease stage 3
Stem cell therapy is considered to be the most advanced one to treat diabetes. For type 1 diabetes, stem cell can differentiate into beta cell, so the insulin can secrete normally and patients can avoid injecting insulin and take in medicine which can lower blood sugar. For type 2 diabetes, stem cell can also repair the damaged beta cells. In addition, once diabetic kidney disease develops into stage 3, there must be damaged and necrotic cells in the kidney. Stem cell can not only repair the damaged cells but also differentiate into the necrotic cells, thus rebuilding renal function.
In addition, stem cells can also enhance the immunity. Diabetes is a kind of immune disorder. So after immune is regulated, stage 3 diabetic kidney disease can not only be controlled but also will not turn worse.

Treat Diabetes with Stem Cells and Herbs in China

Diabetes is usually an immune disease, so it is not easy to treat. Extreme thirst, frequent urination, hunger, blurred vision and fatigue are the common symptoms for Diabetes. As we know, Diabetes refers to the pancreas fails to produce insulin which can adjust the sugar level in blood, thus leading to many symptoms. Therefore, the injection of insulin is the main treatment for patients with Diabetes.
How insulin functions in the body?
It is well known to us that insulin is produced by the pancreas, which helps glucose to move out of the blood into cells throughout the body where it is used for fuel. If there is not enough insulin or the insulin can not work properly to transfer the blood sugar into cells to play as fuel, there would be high blood sugar level. So, it is necessary for patients with Diabetes take insulin to keep sugar level steady. However, patients with Diabetes will resist to injecting insulin for insulin brings them lots of problems. It is inconvenient for them to take the insulin for the medicine should be store in a cold place, such as fridge. To the young patients, they may miss some parties for they need inject insulin before meal. It is better for them heave meal at home. Some patients with Diabetes can not bear the pain for the injection everyday. There are so many problems, so most patients want to take a new treatment which is easy and effective. With the development of Stem Cells, Stem Cells Transplant is applied in treating Diabetes and the effects are good.
With the functions of self-renewing and multiple differentiation, stem cells can repair the damaged pancreatic cells. The main functions of stem cells for treating Diabetes are as following:
1. Improving the secreting ability of insulin. Though most patients with Diabetes have problems with their pancreas when they were born, there are still chance for them to repair it. Stem cells can generate new cells to replace the dead cells, thus recovering the function. In addition, if patients have the disease for less than 5 year, the effects are obviously better than the one who has the disease for a long time. Of course, the specific effects depend on patients' real condition.
2. Changing the immunity of the people.
Diabetes can decrease patients' immunity. We usually meet some patients who said they are sensitive to weather and they are easy to catch a cold. To some degree, Diabetes is a disease on the blood circulation, so it will lead to many complications. If the immunity can be improved, these symptoms can also be relieved. Stem cells have the ability to improve immunity.
3. Promoting blood vessels regeneration ability.
As we said above, Diabetes can do harm to blood circulation, thus leading to series of disease. After transplanting stem cells, the cells can generate blood vessels, thus improving the blood circulation. It is one of the main functions of stem cells.

How to Treat Diabetes with Immunotherapy

For Diabetes, we mainly adopted a systematic immunotherapy consists of immunoadsorption technique, herbal osmotherapy and stem cell therapy to rectify the disorder in insulin secretion and acceptance system. For type 2 diabetes, the pancreas islet secretes insulin, but certain amount of these insulin are of faulty structure. In addition, the whole body immune system in type 2 diabete patient is in disorder, which makes cells insensitive to insulin stimulation.
These two factors contribute to inefficient sugar utilization within body and sugar retention within body. Diabetes itself is not fatal, but the danger exists in various complications that might be caused by high sugar level. For example, inefficient sugar utilization leads to lipid dissolving, and lipid deposition on blood vessels can easily give rise to thrombus. Thrombus in the brain, heart and kidneys are the main causation of diabetic patient's death.
Based on the specific pathology of diabetes, the immunotherapy is adopted to rectify this disorder in insulin secretion and acceptance system. First, herbal therapies are adopted to promote whole body blood circulation and degrade blood stasis to prevent the formation of thrombus. This therapy also enhances self-recuperating ability of immune system. Stem cell therapies focus on restructuring the pancreas islet and enhance pancreas islet secreting normal structure insulin. Stem cell therapy, together with T-reg cell therapy, also enhances cells' sensitivity to insulin to promote insulin utilization within body. Clinical practice has shown a satisfying therapeutic effect, and especially for early stage Diabetic patients.

Blood Sugar in Our Body and Diabetes

Blood sugar mainly refers to the blood glucose in the body. For normal persons, the level of blood sugar is steady. After meal, the level of blood sugar will be a little higher, which will not be higher than 180mg/dl. The FBG( fasting blood sugar) is steady relatively, which is 70-110mg/dl(3.9-6.1mmol/L). All the energy the body needs comes from glucose. So the blood sugar must be enough so that it can meet the need of the body.
The normal range of FBG is 80 to 120 mg%. If it is more than 130, people will suffer high blood sugar. If it is less than 70, people will suffer from low blood glucose. Long time hunger, continuous strenuous work, etc can lead to low blood sugar. At this time, brain tissue will firstly realize it and then people will have dizziness, heart beating faster, hunger and so on.
Sugar is really a necessity which can be gained from grains, fruit and vegetables. After digestion, the sugar will be transformed into monose, and so on and then into blood. It is the source of energy. If it can not be exhausted, it will store in the liver or muscles. If it is too much, sugar will become fat.
For diabetes patients, high blood sugar is the main symptom, which is caused by the insufficiency of insulin secretion. If low blood sugar takes place, it may even threaten diabetics’ life. So controlling blood sugar is very important.

Measles in Nephrotic Syndrome

What is the relationship between measles and Nephrotic Syndrome?
As for this, different experts hold different opinions. Generally,there are two main different ideas.
Firstly, Nephrotic Syndrome is a series of clinical symptoms, which is not a dependent disease. The clinical manifestations are a large amount of proteinuria, edema, low protein in plasma (hypoproteinemia), and hyperlipemia. About 2/3 of adult Nephrotic Syndrome and most children Nephrotic Syndrome are primary Nephrotic Syndrome, which is caused by primary renal glomerular disease, acute renal glomerular disease, progressive renal glomerular disease and so on.
According to what the experts point out, Nephrotic Syndrome is a refractory disease, the inducement of which includes many aspects: such as flu, acute pharyngitis, tonsillitis, nasosinusitis, abscess of gum, scarlet fever, chicken pox, and measles. So, from the above mentioned, we can get a conclusion that measles is a kind of inducement of Nephrotic Syndrome.
Secondly, however, others hold different ideas, thinking that measles is one manifestation of Nephrotic Syndrome, which is caused by allergy. Allergy is caused by weak immune ability of the body. Long time application of hormone can lead to the decrease of immune ability. In addition, hormone can not repair the damaged intrinsic cells, thus treating Nephrotic Syndrome from root.
So patients with Nephrotic Syndrome are suggested to adopt immune therapy in our Hospital, which includes Chinese Medicine, stem cells and so on. Take Chinese Medicine for example. It contains many nutritious and active materials, which can repair the damaged intrinsic cells and increase the immune ability, which is hard to achieve for western medicine for Chinese Medicine can promote the blood circulation, including micro-blood circulation and dissolve the stasis in the blood. In addition, in contrast to the western medicine, it has no side effects, and is easy to operate.
Besides these, patients with Nephrotic Syndrome will also adopt stem cell transplant,which can also increase the immunity and the injection of Treg cell, one stem cell is free of charge.
We believe that, after this, patients with Nephrotic Syndrome will revive the renal function and increase the immune ability. In this case, the symptom measles will disappear accordingly.

How to Feel Good from Nephrotic Syndrome

How to feel good from Nephrotic Syndrome? When Nephrotic Syndrome patients ask this question, they may have had some symptoms. Nephrotic Syndrome is a group of kidney diseases, the damage of which is kidney glomeruli. So the symptoms are mainly a large amount of proteinuria in clinic, the amount of protein in urine per 24 hours is more than 3.5g, low protein in the plasma accordingly, serious edema and high fat in the blood. Among these symptoms, edema and protein in urine is the most obvious, the latter of which shows yellowish foam in urine. With time passing by, Nephrotic Syndrome patients may even have symptoms in digestive system, nerve system and so on.
So to make patients with Nephrotic Syndrome feel good, we should seize the best time to treat. The reason why there is protein in urine is that there is damage in renal glomeruli. In renal glomeruli, we can see filtration membrane. And in filtration, we can see pores, through which, the small molecules can pass through such as creatinine. However, if the basilar is damaged, relatively bigger molecules will also come out, such as protein.
From the above, we can get a conclusion that so as to make patients feel better, we should repair the damaged intrinsic cells especially those in renal glomeruli.
After trying western medicine, patients with Nephrotic Syndrome may find out that their symptoms may also recur after infections, fatigue and so on, which makes them feel headache for they do not want to see the vicious circle take place and want to find a better treatment which can treat it fundamentally and focus on the repairing of intrinsic cells.
Chinese Medicine can make it. Firstly, after Chinese Medicine enters the body, it will promote blood circulation and dissolve the stasis, which can improve the micro-circulation of the kidney. Secondly, it can clear the stasis, and waste things such as immune complex can be out of the body together with urine, which reduce the burden of the kidney. Thirdly, after the first steps, the inner environment can be clearer than before. And the nutritious materials can play roles in repairing damaged intrinsic cells by supplying oxygen, etc. Through this, renal function can be revived.
We believe that after the basilar membrane is damaged, the symptoms will disappear. And patients can feel good.

Treatment Methods for Nephrotic Syndrome

Nephrotic Syndrome is a kidney disorder where there is abnormal leakage of protein in urine, low levels of proteins in blood and swelling of body. Because of the permeability increase of glomerular filtration membrane, a great deal of plasma protein was lost in the urine, which caused the proteinuria of Nephrotic Syndrome. The incidence of this disease ranks second in urinary system diseases, and its clinical features are Albuminemia, much albuminuria, Hypercholeslerolemia and obvious dropsy(oedema or swelling).
The early symptoms of nephrotic syndrome are not obvious. Later symptoms will mainly manifest in palpebrae, and hydrops will appear in splanchnic serouscavity, such as pleural effusion and ascites. The skin will be thin and transparent if the dropsy is serious and will ooze even if slightly damaged. Edema will influence blood circulation, lower the immune response, and infection is very likely to happen. Generally, the treatment for nephrotic syndrome is as follows:
1. western medicine(medication)
As for diminishing symptoms, western medicine has great advantages. Hormonal medicine can alleviate the leaking of the urine protein in a short term and reduce the problems like hypoproteinemia which is caused by too much albuminuria. The application of diuretics can relieve the symptom of body dropsy rapidly. However, hormonal medicine has no curative effect, and even has side effects when used in albuminuria, simple hematuria, acute nephritis caused by severe mesangium proliferative glomerulonephritis, membranous nephropathy of stage 2 or later, membrane hyperplastic nephritis, and focal glomerular sclerosis in addition to chronic renal failure caused by various nephritis.
2. Chinese Medicine(herbs)
Chinese Medicine is a characteristic therapy created by our Hospital after years of clinical practice and research. This kind of therapy mainly aims at the repair of the damaged basement membrane of the kidney, and deals with the kidney fibrosis, and immune complex caused by kidney inflammation. The application of multi-targets measures can reduce the immune response, decrease the side-effects of the medicine, and gradually diminish the clinical dosage of hormone.
3.Stem cell therapy
With nephrotic syndrome developing, renal failure will come into being and there must be sclerotic cells in the kidney, which worsen kidney damage and in this case, there will be less blood flow in the kidney. In this condition, both western medicine and Chinese herbs can not deal with and stem cell can turn the tide, which can differentiate into renal glomerular cells, thus rebuilding renal structure and reviving renal function.

Why Diabetic Nephropathy Patients Have Edema in Lower Limbs?

Why do diabetic nephropathy patients have edema in lower limbs? As we know, one important function of kidney is to filter blood, thus discharging excessive water and keep water balance in the body. However, in diabetic nephropathy, damage in the kidney also takes place, which influences the filtrating ability of the kidney, thus causing edema. Edema can also be called edema, dropsy or swelling, which usually firstly appears in eyelids, ankles and lower limbs.
How does edema come into being for diabetic kidney disease patients?
On one hand, the renal glomerular filtrate rate decreases, but the absorption of water and sodium in renal tubules is normal, which leads to the retention of water and sodium, thus causing the increased permeability of the capillaries in the whole body. In this case, water retention appears in the tissue space. The above condition is usually seen in glomerular nephritis.
On the other hand, with the development of diabetic kidney disease, a large amount of proteinuria appears, in which protein is lost, which leads to low protein in plasma. The osmotic pressure in plasma declines, so liquid flows and edema comes into being. In this case, lower limbs edema will also appear accordingly.
How to deal with or treat edema or dropsy or swelling caused by diabetic nephropathy? In our Hospital, we have researched immunotherapy, which is on the basis of the pathological mechanism of diabetes and kidney disease. Immunotherapy is a combination of both Chinese herbs and western medicine, which can be divided into 6 steps including immune diagnosis, immune clearance, immune blocking, immune tolerance, immune adjustment and immune protection. After these, we believe that edema in lower limbs for diabetic nephropathy can also disappear accordingly.

Diabetics Should Be Alter to High Creatinine

If you are diagnosed with Diabetes for several years, you should be alert to high creatinine level by blood test regularly since it may be connected with kidney damage.
Creatinine is the end products of creatine in muscle and normally it is excreted by kidneys. However, if your kidneys fails to work, a lot of wastes will stay in body, leading to high creatinine. For strong compensatory capacity of kidneys, initially, the creatinine level does not increase at all. It rises until more than 50% renal function has been lost. So, testing blood is a necessity, especially on the level of creatinine, blood urea nitrogen(BUN) and urea acid, etc.
How does Diabetes damage kidney and lead to diabetic kidney disease?
The occurrence of Diabetic Nephropathy is closely connected with high blood sugar or high blood glucose in diabetic patients. If the blood sugar or blood glucose is not controlled well, it will accelerate Diabetic Nephropathy. Well controlled blood sugar can also delay the development of Diabetic Nephropathy. If not controlled well, there will be increased proliferation of renal mesangial cells and increased ECM, thus causing thicker renal glomerular basilar membrane. In clinic, protein in urine and so on will come into being.
How to prevent diabetes developing into diabetic kidney disease with high creatinine ?
1. Uncontrolled blood glucose level is the principle culprit of Diabetes Kidney Disease. You should monitor your blood glucose level regularly and take test four times a day.
2. Controlling blood pressure is a vital part in slowing down Diabetes Kidney Disease progression. You should keep the blood pressure within 130/80 mmHg by taking ACEI or ARB which can lower blood pressure and also has certain effect in preserving renal function.
3. Too much meat consumption can cause more production of creatine, especially lean meat. So keep a low protein intake.

What does Swollen Feet Mean when You Have Diabetes

Why do diabetes patients have swollen feet? Generally, the causes can mainly be divided into two kinds. On one hand, swollen foot is caused by diabetic feet and on the other hand, swollen feet are caused by diabetic nephropathy. Both of them are complications of diabetes.
Firstly, when diabetic feet take place, the damage will occur in feet. Accordingly, blood circulation is blocked. In this case, patients will suffer from edema or have swollen feet.
Secondly, with the long time high blood glucose in the body, there will be blocked micro-blood circulation in the body, including the micro-blood vessels in the kidney. Diabetes kidney disease or diabetic nephropathy will take place. Diabetic nephropathy can be divided into 5 stages in clinic. As we know, one of kidney’s functions is filtrating water. So when kidney is damaged, water can not be filtrated out of the body, thus causing edema or swollen feet.
From the above, we can get a conclusion that we should treat the complications of diabetes especially diabetic nephropathy.
In our Hospital, Chinese Medicine can relieve edema maximally. Firstly, Chinese Medicine can extend blood vessels, improve the blood circulation, which can repair the damaged intrinsic cells and lay a foundation for the stem cell therapy, which is the core therapy in diabetic nephropathy treatment.
Stem cells are initial cells with strong self-renewing and multi-differentiation abilities. They are infused into human body through intravenous injection, and then stem cells will transfer into the kidney lesions by auto-homing function. Stem cells can adjust the immune disorder by repairing the damaged glomeruli and by generating into new renal intrinsic cells to replace the scarred ones.
In addition, stem cells can repair the damaged pancreas islet β cells, thus recovering the function of insulin. In this case, the secretion of insulin can turn normal and diabetes can recover consequently. In this case, swollen feet in diabetic nephropathy can be diminished.

Microalbumin Test and Type 2 Diabetes

In clinic, in most of time, microalbumin is used to monitor the occurrence of kidney disease. The test of microalbumin is the most allergic and reliable index which is used to diagnose kidney disease in the early stage. For normal people, we should test microalbumin once a year. For those who have increased level, they should have a test every three months. In this case, we can have a prevention and timely treatment. As for patients with Type 2 Diabetes, it is more important.
In recent 20 years, the morbidity of Type 2 Diabetes is increasing day by day. At present, all over the world, there are 150 million people are suffering from it, aging from 20 to 79. The countries which rank in front are India, China and America. In total, the number is 70 million. In China, the rate is also increasing year after year.
A large amount of research has proved that Type 2 Diabetes is a risky factor which can even lead to end stage kidney disease, and even cardiovascular disease. In addition, nearly half of patients with Type 2 Diabetes have high blood pressure. Among Type 2 Diabetes, the amount of albumin in urine is the dangerous factor which can lead to death. With the increased density of albumin in the urine, the survival rate decreases. We can also say that microalbumin is the earliest clinical evidence for the diagnosis of diabetic nephropathy.
Once the microalbuminuria of Type 2 Diabetes develops into proteinuria, the renal function will decline further. Generally, when the protein in urine leaks out, it indicates that patients have developed into at least the second stage of Diabetic Nephropathy.
As for the care plan, patients with Type 2 Diabetes should control the intake of sugar, blood pressure and so on. For more information, please consult us online or email us.
In recent years, some authoritative kidney disease experts hold the idea that youngster and adults both should pay attention to the prevention of kidney disease. With people becoming more and more rich, the life quality is increased. Diabetic Nephropathy appears, following high sugar diet, high blood pressure, obesity and so on. Patients who have been diagnosed with Diabetic Nephropathy become younger than those before. So prevention of Diabetic Nephropathy with albumin becomes more and more significant.

How to Treat Diabetes Kidney Disease with Dialysis

How to treat diabetes kidney disease with dialysis? Diabetes kidney disease is a secondary kidney disease which is caused by long time diabetes. When kidney is damaged, creatinine, a metabolism waste can not be discharged out of the body so people take dialysis to help.
There are some differences on when to do dialysis for diabetes kidney disease and other kidney disease patients. For most kidney disease patients, they take dialysis when serum creatinine is as high as 445 umol/L in most of the countries in the world. But for those with diabetes kidney disease, they should take dialysis as soon as the creatinine is as high as 300umol/. Dialysis can really help clear away the inner environment.
On the other hand, dialysis can not treat diabetes kidney disease from root or fundamentally. As we mentioned in the above, diabetes caused kidney damage and we should also treat diabetes. Especially type 1 diabetes is relatively difficulty to treat, which is caused by the insufficiency of insulin secretion. We should not only do dialysis to protect kidney function and do stem cell transplant at the same time. Only in this way, can we treat diabetes kidney disease fundamentally and effectively.
Stem cells are initial cells which can generate and differentiate into those which have become necrotic. When they enter body, they will become beta cells, which can secrete insulin, thus reviving the secretion function. In addition, after they enter kidney, they can also differentiate into renal glomerular basilar membrane for diabetes for a long time damages the basilar membrane in kidney, thus causing the leaking out of protein, etc.
In our Hospital, we also use Chinese Medicine to create a preferred inner environment for the treatment of stem cell.

Prevention of Progression in Diabetic Nephropathy

Once diagnosed with Diabetic Nephropathy, people want to prevent it from progression. To achieve this, we can do as follows:
1. Diabetic Nephropathy is a secondary kidney disease which develops from long time diabetes, which is characterized by high blood sugar in the body. The high blood sugar also damages the kidney in turn, thus causing diabetic nephropathy and other complications eventually. So patients should control blood sugar as well as blood pressure and blood fat so as to prevent progression.
2. Once patients have micro-albumin in urine, patients should take in hypotensor such as ACEI or ARB to relieve the pressure in the renal glomerular capillaries so as to reduce protein in urine.
3. Diabetic Nephropathy patients should also prevent other factors which worsen kidney disease such as avoiding infection, insufficiency of oxygen, and so on.
4. Diabetic Nephropathy patients should also forbid medicine or food which does harm to the kidney.
5. In addition, developing a good life style is also important. For example, stop drinking and smoking, both of them will do harm to the kidney. Report from England said that a doctor analyzed 1239 type 2 diabetes aging from 55 to 81. The investigation lasts for five years and a half. The researchers find out that compared with those who do not take in alcohol or wine, patients who take in alcohol or wine every week have declined eyesight. The heat in alcohol is obviously higher than that of other food, which may lead to the fluctuating of blood sugar, thus accelerating the disorder of sugar metabolism.
6. Timely treatment is also important for patients with Diabetic Nephropathy. Till now, stem cell is widely believed to be the best treatment for stem cell, which can differentiate into beta cells, thus reviving insulin secretion in pancrease and preventing the progression of diabetic nephropathy.

End Stage Renal Disease BUN Creatinine Level

In the end stage of renal disease or uremia stage, both BUN(blood urea nitrogen) and creatinine level will be high. Both of them are metabolism waste which should have been discharged out of the body or else, they will damage the body and give burden to the kidney.
In the end stage of renal disease, BUN is more than 28.6 and serum creatinine is more than 707umol/L. Also, patients will suffer from symptoms in this stage such as fatigue, dizziness, anemia, vomiting, nausea, etc.
In this stage, most patients begin to take dialysis or have been under dialysis for several months to reduce the blood urea nitrogen and serum creatinine. They also take in medicine such as hormone and immunosuppressive agents. How about your effect? Most of us will find out that it can not treat kidney disease fundamentally and some may even think of kidney transplant.
Have you ever thought to try a new one to reduce BUN and creatinine as well as repairing kidney function? I think nearly all of us want to get rid of dialysis and achieve this.
Generally, as long as your GFR (glomerular filtration rate) is more than 20 or is 20 more or less, we can try to let your renal function revive and after this, kidney can filtrate normally and BUN and creatinine can turn normal.
In our Hospital, we mainly use stem cell to help you achieve this. In end stage of renal disease, due to kidney is damaged seriously, there must be both damaged intrinsic cells and necrotic cells in the kidney. Stem Cell Transplant is the latest and effective treatment for end stage of renal disease. Stem cells are initial cells with strong self-renewing and multi-differentiation abilities. They are infused into patients’ body through intravenous injection, and then stem cells will transfer into the kidney lesions by auto-homing function. Stem cells can adjust the immune disorder by repairing the damaged glomeruli and by generating into new renal intrinsic cells to replace the scarred ones. In this case, renal function is rebuilt and BUN and creatinine can be discharged smoothly.
In our Hospital, the stem cell we use is such as cord blood stem cell, mesenchyma stem cell, CIK stem cell and DCCIK stem cell, etc, which are well cultured and has no side effects.

Why does BUN Level Increase?

Why does BUN level increase? BUN is short for blood urea nitrogen, which is a final metabolism of protein. It discharges out of the body through kidney. The normal range of adult BUN is 3.2～7.2 mmol/L(9～20mg/dl). If the examination result is higher than 7.2mmol/L, we consider it is high and long time high blood urea nitrogen will damage the body for it is metabolism waste after all which should have been discharged out of the body. So if the level of blood urea nitrogen is high, it in most of time indicates that there is damage in the kidney. On the other hand, it may also be connected with the excessive intake of protein. Next, we will have a detailed explanation.
1. Too much intake of protein can lead to the high blood urea nitrogen. In the metabolism of protein, NH3 and C02 are produced, which combine into urea in liver. Generally, 1g protein can metabolize 0.3 urea. In addition, the ratio of nitrogen in urea and urea is 28/60. We can also say that the amount of nitrogen is nearly 50%. However, we do not need to be worried for the increased level is temporary and after rest of decreased intake of protein, the level of BUN (blood urea nitrogen) will turn normal.
2. The discharging ability of kidney decreases, which leads to the increase level of BUN(blood urea nitrogen). Kidney is an important organ which discharges urea. After being filtrated in renal glomeruli, urea can be reabsorped in renal tubules. After urea reaches renal tubules, the more the speed the urinating is, the more urea will be discharged out of the body. From the above, we can find out that renal glomeruli and renal tubules are the main renal tissue which influence the discharging of urea.
In renal glomeruli, there is basilar membrane which has pores. Through the pore, small molecules can be discharged. However, when kidney is damaged, the pores will be damaged and urea can not discharge well, thus causing high level of blood urea nitrogen in the blood.

What Are the Symptoms of Kidney Disease with Women

In recent years, due to rapid pace of modern times and work pressure, more and more women get kidney disease with these inducements. If we can find out the symptoms earlier, we can get the best time to treat so as to avoid irreversible condition. Generally, for women, the earlier symptoms are as follows:
1. Due to declined renal function, women kidney disease patients will have less urine, which may be as less as 400 ml in 24 hours. If they take in diuretic, the urine can be more, which, however is just an expedient method. In addition, they can also have increased times of urine at night, which indicates that there is damage in the kidney tubules.
2. In urine, there can also be proteinuria or hematuria in clinic. Hematuria can either be microscopic hematuria or gross hematuria. Proteinuria means proteins leak out of the body into urine. Hematuria means that there are red blood cells in urine. Both of these indicate that the renal glomerular filtration membrane is damaged.
3. Edema is also a symptom in the early stage. A large amount of protein leaking out of the body, the osmotic pressure will be low, which leads to edema. It can also be called by the retention of water and sodium due to the decreased function of kidney.
4. In early stage, kidney’s size will be bigger, which can happen on one kidney or both of the two kidneys.
5. Women kidney disease can also have pain in the kidney, which is for the time being or lasts for a long time. The pain can also be dull.
6. High blood pressure can also be a symptom in the later stage. High blood pressure for a long time can lead to kidney disease. In turn, after kidney is damaged, blood pressure can also be high.

Anaemia Management for People with Chronic Kidney Disease

What is the anaemia management for people with chronic kidney disease? Kidney has a function of secreting EPO, which can stimulate people to generate more red blood cells. After people get chronic kidney disease, the secretion of EPO will be reduced, which leads to less generation of red blood cells, thus causing anaemia in clinic. In this case, patients look pale.
On the other hand, in the end stage of chronic kidney disease, due to the lost of kidney function, many toxins will accumulate into the body, which should have been discharged out of the body. In this case, the toxins in the blood will damage the lifespan of red blood cell, thus accelerate anaemia in clinic.
From the above, we can get a conclusion that if we want to solve the anaemia condition, we should repair the kidney function as well as clear away the toxins in the blood. And we can also know that after anaemia takes place, it indicates that chronic kidney disease patients are in relatively serious stage. And may be people have already begun to take dialysis.
In this case, we should firstly advise people to get blood purification such as hemodialysis, filtration, perfusion, immune absorption, etc so as to create a good inner environment for the red blood cells, which relieve anemia to some extent.
On the other hand, we should also repair the damaged intrinsic cells especially those which can secrete EPO. In this case, the red blood cells can generate. Which medicine can solve the problem? In our Hospital, we mainly use Chinese Medicine and stem cell if necessary for stem cell can differentiate cells which can revive kidney function. Chinese Medicine is applied through osmosis in renal area, after which, the effective herbs will take effect by extending blood vessels, improving the blood circulation, repairing the damaged intrinsic cells. In this way, EPO can generate well and anaemia will be solved fundamentally.

Symptoms of Chronic Kidney Disease Stage 3

According to the GFR(glomerular filtration rate), Chronic kidney disease can be divided into 5 stage. The normal range of GFR is 80 to 120 ml/min. In the third stage, the GFR is 30 to 59 ml/min. Serum creatinine in stage 3 is 186-442umol/l. If eGFR is less than 50%, it indicates that the two kidneys are both damaged and there are also other symptoms in blood such as increased level of urea acid, phosphate and acidity. There are also other symptoms which indicates kidney failure such as malaise, lethargy, oedema (generally swelling of the ankles) and sometimes a loss of appetite.
If not controlled well, the above mentioned therapy will become serious. In addition, serum potassium tends to rise and the blood becomes more acidic. Anemia will appear, which is caused by the following aspects. On one hand, with kidney damaged, the kidney function of secreting EPO will be damaged, which leads to the decrease of red blood cells in the body, thus causing renal anemia. On the other hand, there are more toxins in the blood, which damaged the survival of red blood cells and decrease the life span of red blood cells.
Last but not least, high blood pressure or hypertension will also appear in the late stage 3. It is said that at present there are more than 90 million people in China who are suffering from kidney disease, 30% of whom are caused by high blood pressure. Once kidney is damaged, it can not discharge out the sodium and water, which leads to the retention of water and sodium, thus increasing the blood content and leading to high blood pressure.
It is critical to diagnose and treat chronic kidney disease stage 3 early, which tells us that it is necessary to have regular urine and blood test.

Must Low Back Pain Be Kidney Disease

Must low back pain be kidney disease? As soon as we mention low back pain, many people will hold the idea that it is connected with kidney disease and there must be something wrong in the kidney area. Indeed, kidney lies in the low back of human body. But not all pain in back pain can be caused by kidney disease. And there are many factors which can lead to low back pain besides kidney disease.
1. Some part of the body get injured. For example, when playing basketball, we may sprain the back. If it can not recover easily, we will feel pain in the low back.
2. Tiredness or fatigue due to excessive physical work, which is usually the main reason why we have low back pain. If we sit in front of a computer stand for a long time, we can also feel pain in the back. To our joy, in normal condition, it will recover soon. So in this case, please do not worry so much.
3. Some other diseases can also lead to low back pain. For example, menses of women can lead to pain in the low back as well.
4. When some people are old, they can also feel pain in the low back, which is because osteoporosis.
5. Bad living habit can also lead to low back pain. For example, sleeping in the house which is full of moisture is also bad for the health and may lead to low back pain.
6. Kidney disease can also lead to low back pain. When people are suffering from kidney disease, the intrinsic cells will be damaged and consequently, the filtration membrane will also be damaged. In this case, proteins will leak out, thus causing proteinuria. Protein is an essential element which can assure the activity of human body and play an important role in the metabolism. So if it is lost, many activities will be influenced. The muscles in the back loose the tension force, which limit the movement, so patients will feel pain in the back. In this case, people should go to hospital to have a systematic examination and then take effective treatment.
Especially for those who have had Polycystic Kidney Disease or complex cysts in the kidney, they may feel low back pain easily. Firstly, infection of the cyst will be blame for the pain in the location of kidneys. Secondly, ruptured cyst may play a role in the back pain appearing in people suffering with Polycystic Kidney Disease.
Thirdly,enlargement of cyst is another cause of lower back pain among people suffering from Polycystic Kidney Disease. Sometime, bleeding of the cyst also should be responsible for the pain in the kidneys.

Lupus Nephritis Prognosis

Patients who are diagnosed with Lupus Nephritis will be concerned about the prognosis, wondering how it develops. Generally speaking, several years ago, most patients with Lupus Nephritis could not get a good prognosis if not treated well and about 20% of them would develop into renal failure after 10 years due to the activity of lupus, which makes people desperate.
However, with the medical technology developing, some scholars point out that about 50% of patients with Lupus Nephritis die of the disease. To our surprise, the other 50% patients die from the untoward effects which are caused by treatment such as hormone. Especially in recent years, Lupus Nephritis can be diagnosed earlier, so treatment schedule can be made accordingly, which makes patients with Lupus Nephritis have a better prognosis. So patients with Lupus Nephritis should be confident.
In addition, experts in this field also point out that infection is also an important factor which leads to the death of patients. So preventing infection is also a critical factor which doctors should pay more attention to. Infection prevention has become an important means to control the condition.
From the above, we can get a conclusion that three factors lead to the prognosis, which are activity of lupus, hormone and infection. What measures shall we take? To treat it, we should not use hormone any more and we should choose another one, which we will mainly explain in detail in this passage.
Lupus Nephritis is an autoimmune disease, so we mainly use immunotherapy, which can be divided into six steps: immune diagnosis, immune clearance, immune inhibition, immune tolerance, immune adjustment and immune protection. In these steps, Chinese Medicine is applied, which avoid the side effects which hormones lead in western countries. After these steps, not only immune complex is cleared but also immunity increases, thus stopping the recurrence of Lupus Nephritis.

Alternative Medicine for Lupus Nephritis

There are many medicines in the world which can be used to treat Lupus Nephritis such as glucocorticoid, prednisone, cytotoxic medicine such as cyclophosphamide, immunotherapy and so on. In this passage, we will separately introduce them one by one.
1. glucocorticoid
Glucocorticoid is the main western medicine which is used to treat Lupus Nephritis in the world. After the application, the symptoms can obviously be relieved in clinic. But the principle we should master is that it is based on the specific level of difficult patients and whether there is activities of lupus, which is complex to test.
2. prednisone
The application of prednisone is limited, which is mainly suitable for those whose condition pathological change is severe and their lupus is under activities. The treatment course is long, which can last for at least 1 to 2 years. The attention we should pay attention to is the infection and the retention of water and sodium.
3. cytotoxic medicine such as cyclophosphamide
It is especially suitable for those with diffuse and proliferative type lupus nephritis. It is suitable for those who can not get effective treatment under hormone treatment. During the treatment, we should monitor the blood picture or else untoward effects will take place such as infection, vomiting, nausea, loosing one hair and so on.
4. immunotherapy
Immunotherapy is a therapy on the basis of both Chinese medicine and western medicine. Different from other therapies, it is suitable for nearly all patients with kidney disease especially for the immune disease such as lupus nephritis, which can mainly be divided into six steps: immune diagnosis, immune clearance, immune inhibition, immune tolerance, immune adjustment and immune protection. After immune diagnosis, we can clearly know where the immune complex is, the amount and the type of the immune complex. After the treatment of the other steps, immune reaction can be stopped and immune complex can be cleared away, which can also prevent it from recurring for there is Chinese medicine and stem cell, which can not only repair the damaged intrinsic cells but also increase the immune ability. So it can treat Lupus Nephritis fundamentally.

End stage Renal Disease due to Lupus Nephritis

Lupus nephritis is an inflammation of the kidney caused by systemic lupus erythematosus (SLE), a disease of the immune system. Apart from the kidneys, SLE can also damage the skin, joints, nervous system and virtually any organ or system in the body.
With time passing by, if patients can not receive effective treatment, it will develop into end stage of renal disease, which can also be called uremia. In this stage, there are not only healthy and damaged intrinsic cells but also necrotic cells in the kidney. On the basis of its pathological mechanism, we researched out immunotherapy, which can be divided into 6 steps: immune diagnosis, immune clearance, immune inhibition, immune tolerance, immune adjustment and immune protection.
1. immune diagnosis
After a systematic diagnosis, we can figure out where the immune complex deposits exactly, the amount of immune complex and the exact type of immune response so that doctors can get more scientific diagnosis and arrange better treatment.
2. immune clearance
In immune clearance step, patients with SLE should clear away the immune complex in the blood, which can supply a cleaner inner environment for the treatment of kidney disease. For patients with SLE, the most proper blood purification method is the plasma exchange. Pay attention that the immune complex we clean is the one in the blood not the one on the kidney.
3. immune inhibition
The third one is immune inhibition. There is immune complex which deposit onto kidney, which leads to immune response. Medicine is used, which can stop the excessive immune response, thus stopping the inflammation response at a rapid speed.
4. immune tolerance
After immune inhibition, the immune response can be stopped. And the damage to the kidney can be blocked. However, the immune complex still deposit onto the kidney, which leads to a new series of immune response.
5. immune adjustment
In this step, Chinese medicines are applied, which can improve the blood circulation, including micro-blood circulation and dissolve the blood stasis. In this case, the immune complex can be discharged out, and the immune system can be repaired. Note that in this step, the immune complex we clean is the one on the kidney not the one in the blood. Blood purification such as dialysis and plasma exchange can not achieve this.
6. immune protection
In this stage, we use medicine which can nourish Qi and blood to rebuild the intrinsic immune system. In addition, biochemical cell therapy is also used in clinic such as the transplant of stem cell, which can also help achieve this effect.
After these steps, end stage of renal disease caused by lupus nephritis can relieve and the symptoms will disappear gradually.

Common Symptoms of Lupus Nephropathy

Lupus Nephropathy is a kind of secondary kidney disease which is caused by long time lupus, and the kidney damage mainly takes place in renal glomeruli. Lupus is a kind of auto immune disease, which is caused by the deposition of immune complex in the kidney and the damage of which can spread to many organs in the body in the whole blood system. Lupus Nephropathy is usually seen in women, especially those with young age.
1.Patients with Lupus Nephropathy have red blood cells, white blood cells and protein in urine. With the disease developing, patients may develop into uremia at the end stage. proteinuria is almost existing with different degree edema, About 50% performance for nephrotic syndrome;Contiuning microscopic hematuria is common but there had been no reports of exist alone; 40% had hypertension. About 50% have kidney function decline, it can also result in acute renal failure. Always have renal tubular dysfunction.
2. Hypertention or high blood pressure can often appear when Lupus Nephropathy is severe.
3. Rash, especially butterfly rash on the face can also appear on patients with lupus nephritis.
4. Symptoms in gastrointestinal tract, which are such as nausea, abdominal pain, liver or spleen becoming bigger account for 30-40%.
5. Symptoms in blood system are such as anemia, which is the most common, white blood cells and thrombocytopenia.
6. Cardiovascular anomalies: lesions also involved the endocardial, myocardial and pericardium, and a few can have vasculitis and Renault's phenomenon.
7.Nervous system: the mild involvement is often seen, such as judgment, short-term memory loss, abnormal behavior, a headache. In addition to mental illness, relatively convulsions is rare.
8.Joint symptoms: joint muscle pain, usually involve all the joint of limbs, show the acute inflammatory process.
9.Others: fever, discomfort, weight loss, photosensitive, hair loss and lymph node enlargement, etc.
From the above, we can get the symptoms of Lupus Nephropathy. Realizing it is essential, we should also pay attention to how to treat it. On the basis of its pathological mechanism, experts researched out immunotherapy, which can control and treat Lupus Nephropathy.

How to Treat Lupus Nephritis with Micro-Chinese Medicine Osmotherapy

Lupus Nephritis is a common kidney damage among Systemic Lupus Erythematosus, which is caused by the deposition of immune complex in the kidney. The pathological lesion is mainly in renal glomerular disease, which is also often seen in renal tubules and renal mesenchyme. In renal biopsy, 80% to 90% of patients have damage in kidney. What surprised us most is that 100% percent of them have kidney damage, which shows as Nephritis or Nephrotic Syndrome. Patients with Nephritis have red blood cells, white blood cells and protein in urine. With the disease developing, patients may develop into uremia at the end stage. In renal biopsy, the pathological damage can be divided into Focal hyperplastic glomerulonephritis and Diffuse hyperplastic glomerulonephritis. The former is relatively slight and the latter is relatively severer, and what’s more, it develops progressively and has bad prognosis.
Nephrotic Syndrome caused by Lupus Nephritis shows as membrane renal glomerular nephritis or diffuse hyperplastic glomerulonephritis. As for diffuse hyperplastic glomerulonephritis, besides a large amount of proteinuria, there also exist many other damages such as red blood cells in urine, urinary cylinder and high blood pressure. In some particular cases, slight protein in urine and no kidney disease is found in the latter one.
How about the treatment of Lupus Nephritis?
Conventional treatment and western medicine treatment go as follows:
The common western medicine which is used to treat Lupus Nephritis is such as hormone, immunosuppressant, and so on. Generally, hormone and immunosuppressant are used together to treat symptoms such as controlling the leak out of protein from urine, which leads to hypoproteinemia consequently. Diuretic is used to relieve edema rapidly in Lupus Nephritis patients’ body.
However, just as we point out above, western medicine just focuses on symptoms, which does not emphasize fundamental factors which leads to Lupus Nephritis.
In contrast, Chinese Medicine can achieve better treatment. Chinese Medicine is abstracted from traditional Chinese medicine and has a micro-process compared with traditional Chinese medicine, which means that the use ratio is increased. Secondly, Chinese Medicine is not taken in orally but through osmosis in renal area, which also means that it will not stimulate the stomach and guts, which may lead to poor appetite. Thirdly, Chinese Medicine can promote the blood circulation and dissolve the stasis in the blood, creating a clearer inner environment. Last but not least, Chinese Medicine contains many active and nutritious substances, which can repair the damaged intrinsic cells and prevent proteins and red blood cells, etc from leaking out fundamentally.
Apart from these, patients with Lupus Nephritis should also prevent from sunlight. In summer, remember to wear a hat when you prepare to go out. When you have fever, pain in the joint, protein in urine, lie down and have a good rest. If edema and high blood pressure appear, patients with Lupus Nephritis should keep low salt diet.

Lupus Nephritis Activity Index

The clinical manifestations of Lupus Nephritis has some relationship with its pathological change. Generally speaking, the manifestation of mesangium glomerular nephritis is relatively slight, and there is no abnormal urine, which can appear as latent nephritis. Focal segmental proliferative nephritis can also be called latent nephritis or chronic nephritis. Few of them can exist as Nephrotic Syndrome. Diffuse prolilferative nephritis can also manifest as Nephrotic Syndrome, which accounts for about 75%.
At present, according to the type classification of WHO, it is believed that it can not supply enough judgement for the prognosis and treatment. So later, the activity index is created.
Evaluating the activity index of Lupus Nephritis is a convenient method which can judge how serious the condition is and the activity degree of Lupus Nephritis. In addition, it is also a good evidence which can instruct the draft of clinical treatment. On the basis of experts Ye Zhigao in China, we divide Lupus Nephritis into three levels.
1. If the point is 7 to 10, it indicates that patients are in active activity period.
2. If the point is 3 to 6, it indicates that patients are in moderate activity period.
3. If the point is 1to 3, it indicates that patients are in mild activity period.
4. If the point is less than 1 point, it indicates that the condition is stable, or patients are in quiet stage.
According to the above mentioned, we can use different dosage of hormone, cyclophosphamide, and other medicine such as Chinese medicine to treat it. In western countries, more and more patients are seeking a more effective method which can stop their suffering considering the side effects hormones cause.
Diminishing the above side effects and inheriting the advantages of traditional Chinese medicine, Immunotherapy includes both Chinese medicine, stem cells and some western medicine. It has little side effect and can also focus on the pathological mechanism: immune problem. Further speaking, it can be divided into 6 steps, which includes scientific diagnosis, immune inhibition, immune tolerance, immune adjustment, immune protection and immune clearance.

Treatment for Lupus Eritematoso Sistémico

Lupus Eritematoso Sistémico is a kind of autoimmune disease, which can lead to systematic damage in kinds of organs. The manifestations in clinic are usually fever, red butterfly scar in face, rash, dental ulcer, arthritis, and so on, which are tormenting patients. Patients with Lupus Eritematoso Sistémico are seeking for a better treatment for it.
Firstly, let’s look at the mechanism of Lupus Eritematoso Sistémico. The forming and deposition of immune complex is the main mechanism which leads to kidney damage caused by Lupus Eritematoso Sistémico. Some antigens such as virus from outside and inner antigen such as DNA influence the immune adjustment function, which make beta lymphocyte active and proliferate, thus creating a large amount of autoantibody. They deposit onto the kidney, thus leading to the damage of renal glomeruli.
So from the above, we can get a conclusion that it is the deposition of immune complex that leads to Lupus Eritematoso Sistémico. Of course, the formation of immune complex on the kidney is due to the immune problem.
On the basis of this, in our Hospital, the experts researched out a therapy called immunotherapy, which can be divided into 6 steps mainly. The first one is scientific diagnosis, which helps us find out exactly where the immune complex deposits, and the type of immune complex.
The second step is immune clearance. With the help of dialysis, plasma exchange and so on, the immune complex can be cleared away. Although the immune complex is cleared away, there are also damaged intrinsic cells, which lead to a new circle of immune response. So the third step is immune tolerance, which means our body must try our best to adapt ourselves to the existence of immune complex. At the same time, we try our best to solve the problem. In the fourth step, we use many medicines to adjust the conflicts, which include both western medicine such as stem cell and Chinese medicine such as Chinese Medicine. The main function of Chinese Medicine is to improve the blood circulation, especially the micro-blood circulation, and dissolve the blood stasis, thus increasing the immune ability. In the last step, patients will come into immune protection stage, which means that we use some medicine which can benefit qi and blood, thus increasing the immune.
The above mentioned steps are about the immunotherapy in our hospital. Patients with Lupus Eritematoso Sistémico can relieve better after these.

Systemic Lupus Erythematosus Is Immune Disease

Systemic Lupus Erythematosus is autoimmune disease, about 90% of which can lead to damage in kidney. The cause has not been clear, but the pathogenesis is definite, which can be divided into the following points:
Firstly, in the body of patients with Systemic Lupus Erythematosus, there are kinds of autoantibody such as ones which are used to resist nucleus, resist cytoplasm, and so on.
Secondly, nearly all patients with Systemic Lupus Erythematosus have abnormal immune. B cells in the blood can be highly activated, and a large amount of antibody comes into being, which can lead to antoimmune reaction.
Thirdly, in tissues of Systemic Lupus Erythematosus, we can see the deposition of immune globulin, complement, and DNA. In the eluent, we can see the antibody of DNA.
All the above mentioned indicates that Systemic Lupus Erythematosus is autoimmune disease.
The symptoms of Systemic Lupus Erythematosus are as follows:
Systemic Lupus Erythematosus usually invades many organs and tissues such as skin, joints, kidney, heart, blood and nerve system. The lesions which take place in the organs can take place at the same time and can also take place one by one. The main complaint and symptoms can also be different. The main clinical systems can be fever, butterfly red spot in face, Symmetry joint swelling, pericarditis caused by renal damage, liver damage, symptoms in digestive tract and mental symptoms and so on.
What about the treatment of Systemic Lupus Erythematosus? In western countries, immune inhibiting is used such as hormones and immunosuppressive agent which can stop the excessive immune response. However, as we mentioned in the above articles, when kidney disease takes place, immune complex has deposited in the kidney already. As we know, our kidney need nothing which despite onto the kidney at all. And long time deposition must cause damage in kidney. However, on clearing the immune complex, western medicine can not achieve better treatment. So we should use the combination treatment of western medicine and Chinese medicine.
In our hospital, the experts have researched out a new therapy which can combine the advantages of both western medicine and Chinese medicine. It can be divided into 6 steps: scientific diagnosis, scientific medicine, immune tolerance, immune adjustment and immune protection and immune clearance.

Why Is Lupus Nephrtis an Immune Disease

When somebody is diagnosed with Lupus Nephrtis (Lupus Kidney Disease), doctors will tell the person that he or she has got an immune disease. Why? As we know, people usually have been influenced by many factors before they suffer from Lupus Nephrtis (Lupus Kidney Disease) such as genetic factor, the abnormal amount of hormone secretion, environmental factors such as infection, sunshine shining, change of diet, medicines and so on. Faced with one or two of the above mentioned environmental factors, some will suffer from Lupus Nephrtis (Lupus Kidney Disease) and some will not. Why? It is because of the immune system. Immune system is a system which can protect us and prevent us from getting disease. If the pathological disease is invading us, the immune system will start to work. Those whose immune system is strong enough will not get the disease while those whose immune system is not strong enough will get disease. So from the above, we can get a conclusion that patients with Lupus Nephrtis (Lupus Kidney Disease) has lower immunity compared those who are not allergic to the pathological substances.
Even people are diagnosed with Lupus Nephrtis, (Lupus Kidney Disease) it is not necessary to be nervous for we have researched a systematic and scientific treatment for it, which is called immune treatment. The core techonology of the therapy are as follows:
Firstly, before patients receive treatment, they should receive a scientific treatment because if the diagnosis is wrong, we will treat the disease by mistake, which can not only delay the treatment, but also will worsen the condition. Let alone the money which is spent.
Secondly, after patients with Lupus Nephrtis (Lupus Kidney Disease) receive effective diagnosis treatment, they should receive effective treatment. Nearly 95% percent of kidney diseases are due to immune disorder. And Lupus Nephrtis (Lupus Kidney Disease) is no exception. Among kidney diseases which are related to the immune, most of them are caused by immune reaction. So it is more necessary for doctors and experts to research the treatment of immune medicated kidney disease. A creative treatment which can stop the immune comes out, which can inhibit the immune inflammation response rapidly, and stop the abnormal damage of the intrinsic cells. To achieve it, firstly our treatment is based on the scientific treatment, which can tell the type of immune reaction and find out where the immune complex is.
Thirdly, patients with Lupus Nephrtis (Lupus Kidney Disease) are brought into the stage of immune tolerance. Tolerance means bearing. In other words, it means that human bodies try to adapt themselves to the deposition of pathogenic materials in the kidney. After the immune blocking treatment, although the tissue inflammatory damage and cell damage are stopped, the damaged intrinsic cells and immune complex which deposited in kidney have not been cleared. Based on this, three measures are taken to deal with it.
Fourthly, patients with Lupus Nephrtis (Lupus Kidney Disease) come into immune adjustment stage. Our human body will not allow the long time existence of immune complex and damaged cells. So clearing these abnormal substances is an inborn ability of human body, which is called the rejection ability.
Fifthly, patients with Lupus Nephrtis (Lupus Kidney Disease) come into immune protection stage. Only the above mentioned are not enough, which can not stop the further damage to the kidney. In this step, damaged cells are repaired, damaged tissues are also rebuilt.
Last but not least, patients with Lupus Nephrtis (Lupus Kidney Disease) come into immune clearance treatment, and in this stage, immune absorption, plasma exchange and blood purification is applied.
Maybe from the above mentioned, some can get a conclusion that what we talked about are western medicine treatment. As a matter of fact, firstly, the method is different from western ones, on the other hand, during the whole process, Micro-Chinese Medicine Osmotherapy is applied, which can create a proper treatment environment. The function of anticoagulation, preventing thrombosis of Micro-Chinese Medicine can also make up the insufficiency of immune treatment. In addition, Micro-Chinese Medicine can decrease the side effect in the immune treatment, which can assure the effect of immune treatment.