Friday, July 19, 2013

What are the clinical symptoms of polycystic kidney disease?

Polycystic kidney disease is to be judged by what the symptoms of? Today Xiaobian polycystic kidney disease treatment methods and we talk about a specific content is as follows:

Polycystic kidney disease symptoms appeared in the kidney cortex and medulla urine sample liquid containing numerous cysts were dispersed. There are two genetic forms, one is an autosomal dominant polycystic kidney disease, mostly before the onset of symptoms in adulthood, but it can also be symptoms in the newborn.

1 hypertension is common manifestations of ADPKD, not elevated in serum creatinine before, about half of high blood pressure, which is oppression surrounding tissue cysts, activation of the renin - angiotensin - aldosterone system are related. The past 10 years, Graham PC, Torre V and Chapman AB confirmed that the disease so normal kidney tissue, cysts and cyst adjacent mesenchymal epithelial cells have increased renin granules, and increased renin secretion. These cysts grow on and hypertension are closely related. In other words, those who have high blood pressure cyst growing faster, can directly affect the prognosis.

2 sides nephropathy kidney enlargement progress occurred asymmetry, size differences, to the late two kidneys can fill the entire abdominal cavity, there are many renal cysts cloth surface, so that kidney-shaped irregular, uneven, hard texture.

3 Approximately half of the patients showed microscopic hematuria hematuria may be associated with episodes of gross hematuria, the Department of the cyst wall caused by ruptured blood vessels. Bleeding when blood clots can cause colic through the ureter. Hematuria and proteinuria often accompanied by white blood cells in urine, urinary protein less, generally not more than 1.0g / d. Significant pyuria kidney infection, hematuria aggravated, low back pain with fever.

4 important symptom for kidney pain, lower back often oppressive or dull pain, there will be pain, and sometimes abdominal pain. Pain may be due to physical activity, walking for too long, such as sedentary exacerbated after bed reduce. Renal bleeding, stones or infection is sudden movement causes pain.

5 polycystic liver middle-aged patients with ADPKD found that about half of polycystic liver, approximately 70% after 60 years old. Generally believed that its development is slow, and about 10 years later than polycystic kidney. Its cyst is formed by the lost bile duct dilatation. In addition, pancreas and ovarian cysts may also occur, colonic diverticulitis complicated by a higher rate.

6 renal insufficiency to happen sooner or later the disease renal insufficiency, individual cases that occur in adolescence renal failure, usually before age 40 rarely have renal dysfunction, age 70 remains about half of renal function, but the development of hypertensive patients to greatly shorten the course of renal failure, there are also individual patients 80 years of age can maintain kidney function.

More about polycystic kidney disease introduction on here, hoping to be helpful to everyone, the above is only for reference, please consult a professional doctor.

1 comment:

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