Creatinine What is the real reason for reducing

The kidneys are important organs of the human body, some of the standard evaluation of kidney function is good or bad, we know that some patients with renal failure appears unusually high creatinine phenomenon, but there is a friend that reflect their own low creatinine found in urine creatinine matter how low This is confusing. Creatinine is an important indicator of kidney disease, creatinine instability especially low, very puzzling. Next we take a look at expert creatinine reduce what is the reason.
Experts tell us that the reason is due to the low creatinine in the kidneys by a variety of causes of violations, the first occurrence of impaired renal intrinsic cell phenotype, the formation of pathological changes, stimulate kidney fibroblasts into myofibroblasts, and and stimulate the inherent while violating the normal kidney tissue, the occurrence of the same disease, thus forming a kidney from point to plane, from the local to the whole, the expansion of the spread of excitation-type process to enter the device quality injury period (ie, renal impairment period), this time due to the kidneys continue to cause injury, and the excretion of waste reduced functionality, creatinine and causing accumulation of toxins in the body, which appeared in blood creatinine, blood urea nitrogen, creatinine in urine decreased renal filtration over rate has dropped and so on. While patients will have high blood pressure, high degree of swelling and other symptoms elsewhere in the body.
In addition, the experts pointed out that the human body muscle metabolism creatinine substance is mainly produce creatine, creatinine excretion through the kidneys into the body. Under normal circumstances, the body's muscle mass is relatively stable, the production amount of creatinine is constant, depending on the level of serum creatinine renal excretion of creatinine much. Is worth noting that the compensatory kidney function is very powerful, if both kidneys are normal, as long as one functioning kidney, serum creatinine can be maintained at normal levels. That is, the degree of renal impairment accounted for more than half of the entire kidney, the only cause elevated serum creatinine. Therefore, serum creatinine and does not reflect an early, mild decline in renal function. So found the problem to be solved.
Creatinine is a waste of human excretion, kidney is the main excretory organs, creatinine is likely to be high or low kidney problems. Kidney disease patients in addition to regular treatment, the most important in our daily lives is the prevention and care of patients with kidney disease, only the correct prevention and maintenance in order to alleviate the condition of the kidney patients, early rehabilitation.