Monday, July 8, 2013

Creatinine Rises after Kidney Transplantation in Diabetes

Diabetes is a disease which can affect kidney and develop into kidney failure eventually if diabetes can not be controlled for a long time. In renal failure stage, diabetes patients consider kidney transplant, which can really help relieve to some extent. However, they also find out that some time after kidney transplant, creatinine will also rise. Why? Kidney transplant can not solve the problem from root.
The primary disease diabetes is caused by the immune disorder. Take type 1 as an example. The pathology of Diabetes type 1 is absolutely inadequate secretion of insulin due to the damage to islet cells. The causes of it include hereditary factor and environment factor which cause immune disorder. The abnormal immune response will cause damage to islet cells. In order to treatment this disease, we should first repair the damaged islet cells and at the same time, regulate the immune system. If the immune system can not be regulated, there will still be damage in the body, which will affect kidney sooner or later although patients have done kidney transplant. So creatinine will also rise after kidney transplantation in diabetes.
How to lower creatinine after kidney transplant in diabetes from root? Stem cells are the most primary cells of the human body. After transfused into the patients' body, these stem cells can differentiate into various functional cells needed. The stem cells can differentiate into new islet cells and replace the dead ones, thus recovering the islet function. T-reg cells can help regulate the immune system and stop the attack to healthy islet cells, thus protecting the remaining islet function. After the treatment, the dose of insulin injection can be reduced significantly and some patients can even stop insulin.
So from the above, we can find out that stem cells can make a difference. It can even help those who have planned to do kidney transplant but it is hard to get a donated kidney.

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