Friday, July 26, 2013

Hyperglycemia and diabetic nephropathy

As we all know, high blood sugar caused by the disease and a lot. Diabetic nephropathy is one of them. Which led to the onset of diabetic nephropathy is one important reason is that high blood sugar. Thus hyperglycemia and diabetic nephropathy are closely related.

Hyperglycemia is the major cause of diabetic nephropathy caused, sustained high blood sugar can be formed glomerular perfusion, high filtration, the mesangium, basement membrane, such as capillary endothelial damage; further damage to the glomeruli and tubules ; ultimately lead to glomerular and glomerular arteriosclerosis, causing damage to renal units; cause renal dysfunction.

Diabetic microvascular complications can occur and often accompanied microcirculation of the blood coagulation easy to form clots. Renal microcirculation If thrombosis, renal unit will ischemia and hypoxia, so that increased urinary protein, decreased kidney function, leading to the onset of kidney disease. Also high blood viscosity, blood viscosity and microcirculation of diabetic nephropathy is caused by one of the reasons.

Hyperglycemia in patients are often associated with diseases such as high cholesterol and high blood pressure, high cholesterol can promote glomerulosclerosis, accelerated progression of diabetic nephropathy. Hypertension, renal vascular resistance, the increase in renal blood flow, intrarenal pressure increased, so as to lead to proteinuria, glomerular sclerosis and renal failure.

Diabetes and hypertension often coexist, it will form a vicious circle, in patients with diabetes and hypertension are more prone to kidney damage.

Hyperglycemia and diabetic nephropathy has a close relationship should be avoided during treatment of elevated blood sugar all acts, would like to wish a speedy recovery of patients with a healthy!

1 comment:

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