The treatment of chronic nephritis need to be targeted

Experts say, according to the onset of the chronic nephritis causes and different ways, the treatment of chronic nephritis need to be targeted. So the specific how to do? Here please xian tongji hospital experts to introduce the common treatment methods of chronic nephritis.
Early chronic glomerulonephritis should give corresponding treatment against its pathological types, suppress the immune mediated inflammation, inhibition of cell proliferation, reduce renal sclerosis. And should be to prevent or delay the progressie worsening renal function, improve, or relieve the clinical symptoms and the prevention and treatment of complications for the main purpose. Can adopt comprehensive treatment measures of the following:
1. The active control of high blood pressure. To prevent renal impairment or have impaired renal function improved, prevent cardiovascular complications, and improve the long-term prognosis.
(1) the treatment principles as follows: (1) to achieve the target, such as urinary protein
(2) the method of treatment:
1) non-drug therapy. Limit the intake of dietary sodium, associated with high blood pressure patients should limit sodium, sodium intake in 80 ~ 100 tendency, antihypertensive drugs should be conducted on the basis of the limit sodium diet: adjustment of dietary protein and potassium intake of food. Quit smoking, limit alcohol; To lose weight; Proper exercise, etc. (2) drug therapy. The commonly used antihypertensive drugs with angiotensin converting enzyme inhibitors (ACEI) and angiotensin Ⅱ receptor antagonist (ARB), long-acting calcium channel blockers (CCB), diuretics, beta-blockers, etc. Because the ACEI and ARB in addition to have lower blood pressure function, and reducing urinary protein and delay the renal protective effect of deterioration of renal function, should be preferred.
With ACEI and ARB renal insufficiency patients to prevent high potassium and elevated serum creatinine and serum creatinine greater than 264 mu mol/L (3 mg/dl) must be under strict observation when used carefully, especially pay attention to the monitoring of renal function and prevent high potassium. With ACEI has a persistent dry cough a few patients, adverse reactions, can change with ARB class.
2. Reduce the urine protein. Delay the decline of renal function, proteinuria and renal function impairment are closely related, therefore should be strictly controlled. Effect of ACEI and ARB have lower urinary proteins, the dosage required dose often need higher than the step-down. But should prevent the occurrence of low blood pressure.
3. Limit the intake of protein in the food, and phosphorus. Low protein and low phosphorus diet can reduce glomerular high pressure, high perfusion with high filtration, delay the glomerular sclerosis. Renal insufficiency nitrogen qualitative hematic disease patients should limit the intake of protein and phosphorus, high quality or low protein diet added with essential amino acids or alpha - keto acid.
4. Avoid aggravating factor of renal damage. Infection, low blood volume, dehydration, fatigue, water and electrolyte and acid-base balance disorders, pregnancy and application nephrotoxicity drugs (such as amino glucoside antibiotics and nonsteroidal anti-inflammatory drugs (nsaids), contrast agents, etc.), are likely to damage the kidney, should avoid to use or careful.
5. Corticosteroids and cytotoxic drugs. Due to chronic nephritis is including a variety of diseases, clinical syndrome, its etiology, pathological type and its degree, clinical manifestation and kidney function difference is bigger, so whether the application of glucocorticoid and cytotoxic drugs should be determined depending on the type of etiology and pathology.
6. Other. , anticoagulants and antiplatelet aggregation drug statins lipid-lowering drugs, traditional Chinese medicine can also be used.
The above is our experts to obtain specific therapy of chronic nephritis professional analysis, if you have any doubt, can consult our experts online, xi 'an tongji kidney disease hospital opened a green channel network to make an appointment for you, the input problem, click the ask button, immediately ask professional nephrologist. Details please consult experts free telephone: 400-8899-8899 (mobile) free health advice 24 hours a day. Hospital address: xi 'an mayor annan road no. 16 (800 m) tower to the south.