What Can Lead to the Damage to CKD

The factors which can lead to the damage to CKD are as follows:
Anger and bad mood
Anger and bad mood can lead to the increased secretion of materials which can shrink the blood vessels. What’s worse, it can also influence the clearance function of white cells and phagocyte and reduce the blood flow in the kidney, leading to the insufficiency of blood and oxygen in the kidney, giving more burden to the kidney.
Tirdness
Liver is used to dissolve toxins and kidney is used to discharge toxins. Most metabolism which is produced in the body will discharge from kidney. When chronic kidney disease patients are too tired, the adjustment ability will decrease, the protection ability will decrease, which can worsen renal insufficiency.
High blood pressure
Besides allergic reaction which can lead to the inflammatory reaction and bacteria infection, in clinic, high blood pressure is also a factor which can worsen chronic kidney disease. After the blood pressure increases, the blood vessels in all levels of arteries will shrink, which leads to the insufficiency of blood and oxygen in the kidney and renal fibrosis starts. With more and more kidney units damaged, renal failure deteriorates, which even may develop into uremia.
Long time high blood sugar
Long time high blood sugar can damage levels of blood vessels. It can also lead to thinner lumen and form thrombosis. In this case, the blood supply to kidney will decrease. Long time high blood glucose can also increase the thickness of basilar membrane, make the lumen of arteries become marrow. The endothelial cells can also relieve materials which can shrink the blood and lead to the insufficiency of blood and oxygen in the kidney.