FSGS, short for Focal Segmental Glomerulosclerosis, is a genetic abnormality
that influences renal glomerulus. The scar tissue covers the body's filtration
system, which leads to chronic renal failure. What is the cause of FSGS?
Basically doctors do not know very clear. There may even be several different
diseases that cause the same appearance in the kidney. It seems that the general
cause of FSGS is immunological. That is, the antibodies and white blood cells we
have to fight off infection cause some damage to our own bodies by mistake. In
FSGS any damage is usually only in the kidneys, so the rest of you should be
alright. In a few cases the condition seems to run in families, but this is
uncommon.
In China, doctors divided FSGS into primary one and secondary one. For the
former, the reason is not clear, and for the latter, it means FSGS happens after
some other disease lasts for a long time which is not treated well. As for the
secondary kidney disease, we divided it into three kinds.
1. renal glomerular disease.
It means that FSGS is caused by long time diabetes, hereditary nephtitis, IgA
nephritis, etc.
2. renal tubules-interstitial disease.
It means that FSGS is caused by reflux nephropathy, radiation nephritis,
etc.
3. Other renal insufficiency diseases.
FSGS (Focal Segmental Glomerulosclerosis) can take place in any age, among
which, young men take up a lot. The symptoms are mainly nephrotic syndrome,
which takes up about 50%. Proteinuria mainly is continuous or selective. 50% to
60% of patients have hematuria. High blood pressure and renal damage vary
according to different persons’ specific condition. The prognosis is closely
related to the level of proteinuria.
No comments:
Post a Comment