Henoch-Schonlein Purpura with Skin Rash and Nephrotic Syndrome

What’s henoch-schonlein purpura? Why is there skin rash in henoch-schonlein purpura? What’s the relationship between henoch-schonlein purpura and Nephrotic Syndrome? Allergic purpura is short for henoch-schonlein purpura. It is a kind of small vessel vasculitis which is caused by the lesion of blood vessels. The wall of the blood vessels get damaged, then the permeability of blood vessel walls increases, which lead to the leak out of red blood vessels and the form of purpura. When people stand, the venous pressure of lower limbs is higher than that of upper limbs. The exercise of muscles in lower limbs is more than that in lower limbs. After movement, the muscles shrink, which leads the inner pressure to increase. Inner pressure in partial small blood vessels and capillaries increase suddenly, so the back flow of veins is blocked and the vein is in the insufficiency of oxygen, which leads to the damage of blood vessels wall, causing bleeding. In this case, purpura comes into being.
What’s the relationship between purpura and skin rash? Skin rash is actually one symptom of purpura. Besides this, patients with purpura can also suffer from respiratory tract infection, fever, headache, fatigue, and so on. Among them, skin rash is a common symptom. In addition, patients with purpura can also be accompanied by pain in belly, diarrhea, vomiting, hematochezia. What’s more, patients can also suffer from kidney damage at the same time. In other words, kidney can be involved in the damage caused by small vessel vasculitis. So what’s the relationship between purpura and Nephrotic Syndrome?
As we mentioned above, we know that purpura can cause damage to kidney. Nephrotic Syndrome is a kind of kidney disease, which is a group of renal glomerular disease. The characteristics of Nephrotic Syndrome is large amount of proteinuria (protein which leaks out into urine every day is more than 3.5g.), hypoalbuminemia, (which is less than 30g /L), hyperlipemia and serious edema. In a word, if patients with purpura have had the above mentioned symptoms, they will be diagnosed with Nephrotic Syndrome.
Once patients have purpura, they should take care of themselves. At first, do enough exercise and prevent themselves from catching a cold so as to enhance the resistance. Secondly, have enough rest and avoid fatigue. Thirdly, smoking and alcohol should be forbidden as well. Last but not least, pay attention to the diet. Avoid pepper especially sea food which can lead to allergic reaction. In addition, keep far from allergen.
All in all, skin rash is a symptom of purpura and Nephrotic Syndrome is a complication caused by purpura.