Talk about the prognosis of chronic glomerulonephritis

The prognosis of chronic glomerulonephritis? This is a lot of chronic nephritis patients want to know, down a concrete analysis of experts from xi 'an tongji hospital following the prognosis of chronic nephritis.
Chronic glomerulonephritis abbreviation for chronic nephritis, refers to the proteinuria, hematuria, hypertension, oedema as basic clinical manifestations, way is different, the onset of the disease, pathological changes slow progress, can be different degree of renal impairment, will eventually develop into a group of glomerular disease of chronic renal failure. Due to this disease of pathological type and different period, the main clinical manifestations of each are not identical, diseases are diversified.
The effect of prognosis of chronic glomerulonephritis are:
(1) pathological factors:
1) pathological types: mild mesangial proliferative glomerulonephritis, good prognosis in severe mesangial proliferative glomerulonephritis and membrane proliferative glomerulonephritis, focal segmental glomerular sclerosis, prognosis is poorer; Membranous nephropathy, prognosis is good, progress has been slow.
(2) chronic indicators: the number of fibrous crescents, glomerular sclerosis, the degree of interstitial fibrosis, and the number of how many of the renal tubular atrophy associated with prognosis. The above indexes, the more the worse the prognosis.
(3) in the renal vascular disease serious prognosis is poor.
Lesion lighter nephron compensatory hypertrophy; In sometimes visible between glomerular hypertrophy of glomerular sclerosis, generally has the following several types: (1) mesangial proliferative glomerulonephritis;
(2) membrane hyperplastic nephritis;
(3) focal proliferative glomerulonephritis.
(4) membranous nephropathy;
(5) or focal segmental glomerular sclerosis. The lesions develop gradually, and ultimately lead to severe damage of renal tissue, formation of end-stage kidney pyknosis.
Chronic glomerulonephritis prognosis? The disease is common, especially in young male high incidence in young adults. Expert introduction, chronic nephritis prognosis mainly include: chronic nephritis can be late for the development of renal dysfunction and renal failure, can appear in patients with anemia, heart failure, etc. Its mainly by renal parenchyma damage, erythropoiesis and malnutrition. Such as anemia, and heart failure severity is proportional to the kidney disease and renal impairment.
The pathological changes of chronic nephritis is two kidney diffuse glomerular lesions. Due to chronic inflammatory process, glomerular capillary undermine, fibrous tissue hyperplasia; Glomerular fibrosis, hyaline, form the structure of glass sample pellets. The blocked blood flow to glomerular, renal tubular atrophy, fibrosis, and interstitial fibrous tissue hyperplasia, lymphocyte infiltration.
Renal biopsy pathology classification to more reliable on the judgment of the prognosis, it is generally believed tiny lesions in the kidney disease and pure mesangial hyperplastic nephritis prognosis is good, membranous nephropathy progress is slow, the prognosis is good membrane hyperplastic nephritis, the latter in a few years in most of the cases of renal insufficiency, focal segmental glomerular sclerosis prognosis is poor.
In recent years, studies have shown that in addition to glomerular lesions, renal tubule and renal blood vessels and the degree of renal interstitial lesions significantly affect the prognosis. The small blood vessels in the renal tubular atrophy, renal sclerosis, renal interstitial a large number of lymphocyte infiltration and interstitial fibrosis, the prognosis is poor.
Chronic glomerulonephritis prognosis? Above all is the specialist for the prognosis of chronic nephritis.