Diabetic Nephropathy is a kind of disease which damages both kidney and other
organs in the whole body. So it is necessary to have an earlier diagnosis so as
to prevent more damage. Which examinations should people take to diagnose
whether they have had Diabetic Nephropathy?
Generally, the examinations which they should take to diagnose Diabetic
Nephropathy are as follows:
The first one is physical examination.
Patients with Diabetic Nephropathy can have different degree of high blood
pressure, edema, and even ascites, hydrothorax and so on. In addition, they also
have complication of Diabetic Retinopathy. The above mentioned are about the
common diagnosis of Diabetic Nephropathy.
The second one is assistant examination, which includes the following
aspects.
1. glucose
Glucose is an easy way to judge whether people have Diabetes. Diabetic
Nephropathy can be false negative or false positive, which is the main diagnosis
evidence of Diabetic Nephropathy.
2. urinary albumin excretion rate (UAER)
Urinary albumin excretion rate is an important index which can be used to
diagnose early-stage Diabetic Nephropathy. When the urinary albumin excretion
rate is more than 200μg/min, or when TUPr is more than 0.5g/24h, people can be
diagnosed with Diabetic Nephropathy. Generally, the sediment in the urine is not
obvious. When there are more white blood cells, it indicates urinary tract
infection. When there are enough red blood cells, it indicates that there is
hematuria caused by other reasons.
3. At the end stage of Diabetic Nephropathy, patients can also have decreased
clearance rate of endogenous creatinine, increased blood urea nitrogen and
increased serum creatinine.
4. At the early stage of Diabetic Nephropathy, patients can have increased
glomerular filtration rate and increased kidney size. But in uremia stage, the
size of kidney does not become smaller obviously.
5. To diagnose Diabetic Nephropathy, people should also have examination of
eye ground. They should also have a fundus imaging, which can show the diabetic
eye lesion such as microaneurysm.
Last but not least, people who have Diabetes should monitor the blood sugar
strictly, because long time high blood sugar will lead to damage in kidney
easily.
Wednesday, June 5, 2013
Tuesday, June 4, 2013
How does Diabetes Affect Kidney Function
Once diagnosed with diabetes, patients are reminded to take care by their
doctor for it may affect kidney function and develop into kidney disease some
day. How does diabetes effect kidney function? We should explain it from two
aspects.
On one hand, high blood glucose is the main and typical symptom of diabetes. However, long time high blood sugar can decline immunity, and lead to the disorder of immune defense. In addition, long time blood glucose can also lead to dense plasma, which makes the micro-blood vessels blocked, and further influencing the blood vessels in the whole blood system, kidney blood vessels included. With time passing by, renal insufficiency takes place and renal function is effected.
On the other hand, one complication of diabetes is high blood pressure. On the basis of cytology, Hypertensive Nephropathy is a kind of kidney disorder, the damage of which is endothelial cell because of insufficiency of blood. When patients are in hypertension or high blood pressure condition, blood pressure will not keep stable, which rises or decreases suddenly. In this case, the rising and falling blood pressure will stimulate the renal glomerular capillaries, which leads the wall of the renal glomerular to suffer from more pressure. The capillary walls suffer from brushing, which leads the lumen of renal capillary to become narrower, thus causing renal insufficiency. In this condition, the renal glomerular capillaries will be damaged, which attracts the infiltration of inflammatory cells. Long time filtration will make the structure of the cells change. Then, the renal glomerular filtration function will be damaged, thus causing kidney failure, and kidney function is effected at the same time.
From the above, we have a general view on how diabetes effects kidney function. Since having had been effected, we should take measures to treat.
On one hand, high blood glucose is the main and typical symptom of diabetes. However, long time high blood sugar can decline immunity, and lead to the disorder of immune defense. In addition, long time blood glucose can also lead to dense plasma, which makes the micro-blood vessels blocked, and further influencing the blood vessels in the whole blood system, kidney blood vessels included. With time passing by, renal insufficiency takes place and renal function is effected.
On the other hand, one complication of diabetes is high blood pressure. On the basis of cytology, Hypertensive Nephropathy is a kind of kidney disorder, the damage of which is endothelial cell because of insufficiency of blood. When patients are in hypertension or high blood pressure condition, blood pressure will not keep stable, which rises or decreases suddenly. In this case, the rising and falling blood pressure will stimulate the renal glomerular capillaries, which leads the wall of the renal glomerular to suffer from more pressure. The capillary walls suffer from brushing, which leads the lumen of renal capillary to become narrower, thus causing renal insufficiency. In this condition, the renal glomerular capillaries will be damaged, which attracts the infiltration of inflammatory cells. Long time filtration will make the structure of the cells change. Then, the renal glomerular filtration function will be damaged, thus causing kidney failure, and kidney function is effected at the same time.
From the above, we have a general view on how diabetes effects kidney function. Since having had been effected, we should take measures to treat.
Diet for Diabetes 7 Years, Creatinine 1.6
If creatinine is 1.6, it indicates that diabetes has damaged kidney for in
normal condition, the creatinine level is 0.6 to 1.2. Here are some suggestions
on daily diet.
1.Low potassium diet, do not eat food containing high-level potassium like edible fungus, potato, sweet potato, Chinese cabbage, dates, banana, orange, yiner (white fungus), peach, apricot,spinach.
2.low salt diet ,do not eat things like soda biscuit , soy sauce, steamed oily sticks, especially for patients who has swelling symptoms and unstable hypertension .
3.Low-phosphate diet ,do not eat seafood and plant in the sea, kelp, dried purple seaweed ,animal abdomen organs, sesame, tea, honey, egg yolk.
4.Low fat diet. Do not eat fat, greasy food, fast food, use vegetable oil instead of animal oil when cooking.
5.High-quality low-protein food. Vegetable oil is not advisable, do not eat bean products like tofu, soy bean, milk powder, sunflower seeds, walnut, peanut and dried fruit. You can have a proper amount of egg white, and milk.
6.High vitamin diet. You can eat food rich in fiber and fruits like pear, apple, cucumber,tomato, etc.
7.No spicy food (ginger, onion, garlic). No smoking.
Last but not least, patients should keep low sugar diet or else, it will worsen blood sugar. What’s more, patients will diabetes should also monitor blood sugar. Low blood sugar is more serious, which may even threaten people’s life.
1.Low potassium diet, do not eat food containing high-level potassium like edible fungus, potato, sweet potato, Chinese cabbage, dates, banana, orange, yiner (white fungus), peach, apricot,spinach.
2.low salt diet ,do not eat things like soda biscuit , soy sauce, steamed oily sticks, especially for patients who has swelling symptoms and unstable hypertension .
3.Low-phosphate diet ,do not eat seafood and plant in the sea, kelp, dried purple seaweed ,animal abdomen organs, sesame, tea, honey, egg yolk.
4.Low fat diet. Do not eat fat, greasy food, fast food, use vegetable oil instead of animal oil when cooking.
5.High-quality low-protein food. Vegetable oil is not advisable, do not eat bean products like tofu, soy bean, milk powder, sunflower seeds, walnut, peanut and dried fruit. You can have a proper amount of egg white, and milk.
6.High vitamin diet. You can eat food rich in fiber and fruits like pear, apple, cucumber,tomato, etc.
7.No spicy food (ginger, onion, garlic). No smoking.
Last but not least, patients should keep low sugar diet or else, it will worsen blood sugar. What’s more, patients will diabetes should also monitor blood sugar. Low blood sugar is more serious, which may even threaten people’s life.
Diet after Diabetes Develops into Diabetic Nephropathy
What is the diet after diabetes develops into diabetic nephropathy?
1. Restrict the intake of Protein: long term of high-protein diet can aggravate the condition of high filtration state, lead to increased metabolin of poisonous nitrogen products and cause the retention of those poisonous products, which further damages the injured kidney. So Diabetic Nephropathy patients are suggested to properly restrict the intake of protein, avoiding the condition mentioned above. In order to relieve the burden of kidney, patients should take high quality protein and have a low protein diet, such as lean meat, egg, milk, fish, etc.
2.Energy: when patients take a low protein diet, they should insure the energy supplement of the body to keep the normal physiological requirements.
3. Low-fat diet: patients at end-stage of renal disease (ESRD) can suffer lipoidosis, so they should take low-fat diet such as olive oil or arachis oil, which contains much unsaturated fatty acid.
4. Restrict the intake of salt: patients when they suffer Hypertension or other obvious symptoms such as edema or decreased urine volume, they should restrict the salt intake, which can relieve the symptom. However, when patients have those symptoms such as vomiting, diarrhea, they should not strictly restrict salt or even supplement salt.
5. Water intake: when patients don not have obvious symptom of edema, they should not restrict water and they need some more water to discharge the waste products in body. However, when there are symptoms of obvious edema, oliguria, anuria, patients should restrict water intake. Otherwise, masses of water intake will aggravate burden to kidney. As a result, ESRD patients should restrict water intake according to urine volume. In addition, when patients suffer fever, diarrhea, vomiting, they should supplement more water.
6. Potassium intake: patients should not restrict the intake of potassium when it is in normal range. However, potassium should be restricted when patients suffer Hyperkalemia and when they suffer Hypokalemia patients should supplement potassium. high-potassimum food such as spinach, bananas, fungus, bean products.
Other substances such as calcium, phosphorus: when kidney is damaged, the discharge of phosphorus will be reduced, leading high level phosphorus. In addition, the injured kidney can also lead to the declined generation of vitamin D3, which affects the absorb of calcium. When the calcium in blood is in a low level, it can easily lead to osteoporosis. So the ideal diet should contain more calcium but less phosphorus. A low protein diet can reduce the intake of phosphorus.
More information about diet after diabetes develops into diabetic nephropathy, please communicate with us online or email us.
1. Restrict the intake of Protein: long term of high-protein diet can aggravate the condition of high filtration state, lead to increased metabolin of poisonous nitrogen products and cause the retention of those poisonous products, which further damages the injured kidney. So Diabetic Nephropathy patients are suggested to properly restrict the intake of protein, avoiding the condition mentioned above. In order to relieve the burden of kidney, patients should take high quality protein and have a low protein diet, such as lean meat, egg, milk, fish, etc.
2.Energy: when patients take a low protein diet, they should insure the energy supplement of the body to keep the normal physiological requirements.
3. Low-fat diet: patients at end-stage of renal disease (ESRD) can suffer lipoidosis, so they should take low-fat diet such as olive oil or arachis oil, which contains much unsaturated fatty acid.
4. Restrict the intake of salt: patients when they suffer Hypertension or other obvious symptoms such as edema or decreased urine volume, they should restrict the salt intake, which can relieve the symptom. However, when patients have those symptoms such as vomiting, diarrhea, they should not strictly restrict salt or even supplement salt.
5. Water intake: when patients don not have obvious symptom of edema, they should not restrict water and they need some more water to discharge the waste products in body. However, when there are symptoms of obvious edema, oliguria, anuria, patients should restrict water intake. Otherwise, masses of water intake will aggravate burden to kidney. As a result, ESRD patients should restrict water intake according to urine volume. In addition, when patients suffer fever, diarrhea, vomiting, they should supplement more water.
6. Potassium intake: patients should not restrict the intake of potassium when it is in normal range. However, potassium should be restricted when patients suffer Hyperkalemia and when they suffer Hypokalemia patients should supplement potassium. high-potassimum food such as spinach, bananas, fungus, bean products.
Other substances such as calcium, phosphorus: when kidney is damaged, the discharge of phosphorus will be reduced, leading high level phosphorus. In addition, the injured kidney can also lead to the declined generation of vitamin D3, which affects the absorb of calcium. When the calcium in blood is in a low level, it can easily lead to osteoporosis. So the ideal diet should contain more calcium but less phosphorus. A low protein diet can reduce the intake of phosphorus.
More information about diet after diabetes develops into diabetic nephropathy, please communicate with us online or email us.
Diet after Diabetes Develops into Diabetic Nephropathy
What is the diet after diabetes develops into diabetic nephropathy?
1. Restrict the intake of Protein: long term of high-protein diet can aggravate the condition of high filtration state, lead to increased metabolin of poisonous nitrogen products and cause the retention of those poisonous products, which further damages the injured kidney. So Diabetic Nephropathy patients are suggested to properly restrict the intake of protein, avoiding the condition mentioned above. In order to relieve the burden of kidney, patients should take high quality protein and have a low protein diet, such as lean meat, egg, milk, fish, etc.
2.Energy: when patients take a low protein diet, they should insure the energy supplement of the body to keep the normal physiological requirements.
3. Low-fat diet: patients at end-stage of renal disease (ESRD) can suffer lipoidosis, so they should take low-fat diet such as olive oil or arachis oil, which contains much unsaturated fatty acid.
4. Restrict the intake of salt: patients when they suffer Hypertension or other obvious symptoms such as edema or decreased urine volume, they should restrict the salt intake, which can relieve the symptom. However, when patients have those symptoms such as vomiting, diarrhea, they should not strictly restrict salt or even supplement salt.
5. Water intake: when patients don not have obvious symptom of edema, they should not restrict water and they need some more water to discharge the waste products in body. However, when there are symptoms of obvious edema, oliguria, anuria, patients should restrict water intake. Otherwise, masses of water intake will aggravate burden to kidney. As a result, ESRD patients should restrict water intake according to urine volume. In addition, when patients suffer fever, diarrhea, vomiting, they should supplement more water.
6. Potassium intake: patients should not restrict the intake of potassium when it is in normal range. However, potassium should be restricted when patients suffer Hyperkalemia and when they suffer Hypokalemia patients should supplement potassium. high-potassimum food such as spinach, bananas, fungus, bean products.
Other substances such as calcium, phosphorus: when kidney is damaged, the discharge of phosphorus will be reduced, leading high level phosphorus. In addition, the injured kidney can also lead to the declined generation of vitamin D3, which affects the absorb of calcium. When the calcium in blood is in a low level, it can easily lead to osteoporosis. So the ideal diet should contain more calcium but less phosphorus. A low protein diet can reduce the intake of phosphorus.
More information about diet after diabetes develops into diabetic nephropathy, please communicate with us online or email us.
1. Restrict the intake of Protein: long term of high-protein diet can aggravate the condition of high filtration state, lead to increased metabolin of poisonous nitrogen products and cause the retention of those poisonous products, which further damages the injured kidney. So Diabetic Nephropathy patients are suggested to properly restrict the intake of protein, avoiding the condition mentioned above. In order to relieve the burden of kidney, patients should take high quality protein and have a low protein diet, such as lean meat, egg, milk, fish, etc.
2.Energy: when patients take a low protein diet, they should insure the energy supplement of the body to keep the normal physiological requirements.
3. Low-fat diet: patients at end-stage of renal disease (ESRD) can suffer lipoidosis, so they should take low-fat diet such as olive oil or arachis oil, which contains much unsaturated fatty acid.
4. Restrict the intake of salt: patients when they suffer Hypertension or other obvious symptoms such as edema or decreased urine volume, they should restrict the salt intake, which can relieve the symptom. However, when patients have those symptoms such as vomiting, diarrhea, they should not strictly restrict salt or even supplement salt.
5. Water intake: when patients don not have obvious symptom of edema, they should not restrict water and they need some more water to discharge the waste products in body. However, when there are symptoms of obvious edema, oliguria, anuria, patients should restrict water intake. Otherwise, masses of water intake will aggravate burden to kidney. As a result, ESRD patients should restrict water intake according to urine volume. In addition, when patients suffer fever, diarrhea, vomiting, they should supplement more water.
6. Potassium intake: patients should not restrict the intake of potassium when it is in normal range. However, potassium should be restricted when patients suffer Hyperkalemia and when they suffer Hypokalemia patients should supplement potassium. high-potassimum food such as spinach, bananas, fungus, bean products.
Other substances such as calcium, phosphorus: when kidney is damaged, the discharge of phosphorus will be reduced, leading high level phosphorus. In addition, the injured kidney can also lead to the declined generation of vitamin D3, which affects the absorb of calcium. When the calcium in blood is in a low level, it can easily lead to osteoporosis. So the ideal diet should contain more calcium but less phosphorus. A low protein diet can reduce the intake of phosphorus.
More information about diet after diabetes develops into diabetic nephropathy, please communicate with us online or email us.
Monday, June 3, 2013
Hypercholesterolemia in Renal Disease
What will happen if hypercholesterolemia appears in patients with renal
disease? Will renal disease cause hypercholesterolemia? What’s the relationship
between hypercholesterolemia and renal disease?
1. How does kidney disease cause hypercholesterolemia?
Influenced by renal fibrosis degeneration, the renal glomerular filtration barrier is damaged. A large amount of plsma protein is lost in urine, which leads to the occurrence of hypoproteinemia. Human beings have a whole self-regulatory mechanism. When the plasma is lost to an abnormal range, human beings will adjust the compensation of liver, and begin the process and combination of protein so as to add the lost proteins. In this case, liver combines excessive lipoprotein, which leads to the fact that lipoprotein is transfused into blood. In this case, hypercholesterolemia which is caused by the lost of large amount of protein comes into being.
2. How does hypercholesterolemia influence kidney disease?
As we know, when kidney problem takes place, there must be insufficiency of blood and oxygen in the capillaries, which will lead to sclerosis of capillaries for a long time. In this case, if hypercholesterolemia takes place, it will worsen the kidney capillary sclerosis and accelerate the renal damage.
What shall we do if we both have hypercholesterolemia and kidney damage? We should firstly decrease the level of hypercholesterolemia. The therapy we can choose is such as Chinese Medicine. It contains active substances which is abstracted from natural herbs and can improve the blood circulation, including micro-blood circulation. Secondly, the effective medicine can help dissolve the blood stasis and discharge them out, thus decreasing the level of hypercholesterolemia fundamentally.
After the level of hypercholesterolemia turn normal, there will be a cleaner inner environment for the repair of the damaged intrinsic cells in the kidney. In this condition, we can apply Chinese Medicine once more, the effective medicines of which can repair the damaged intrinsic cells in the kidney, thus help rebuilding renal function.
1. How does kidney disease cause hypercholesterolemia?
Influenced by renal fibrosis degeneration, the renal glomerular filtration barrier is damaged. A large amount of plsma protein is lost in urine, which leads to the occurrence of hypoproteinemia. Human beings have a whole self-regulatory mechanism. When the plasma is lost to an abnormal range, human beings will adjust the compensation of liver, and begin the process and combination of protein so as to add the lost proteins. In this case, liver combines excessive lipoprotein, which leads to the fact that lipoprotein is transfused into blood. In this case, hypercholesterolemia which is caused by the lost of large amount of protein comes into being.
2. How does hypercholesterolemia influence kidney disease?
As we know, when kidney problem takes place, there must be insufficiency of blood and oxygen in the capillaries, which will lead to sclerosis of capillaries for a long time. In this case, if hypercholesterolemia takes place, it will worsen the kidney capillary sclerosis and accelerate the renal damage.
What shall we do if we both have hypercholesterolemia and kidney damage? We should firstly decrease the level of hypercholesterolemia. The therapy we can choose is such as Chinese Medicine. It contains active substances which is abstracted from natural herbs and can improve the blood circulation, including micro-blood circulation. Secondly, the effective medicine can help dissolve the blood stasis and discharge them out, thus decreasing the level of hypercholesterolemia fundamentally.
After the level of hypercholesterolemia turn normal, there will be a cleaner inner environment for the repair of the damaged intrinsic cells in the kidney. In this condition, we can apply Chinese Medicine once more, the effective medicines of which can repair the damaged intrinsic cells in the kidney, thus help rebuilding renal function.
The Pathogeny for Diabetic Nephropathy
The pathogeny for Diabetic Nephropathy(DN) generally include the following
points:
1. Increase on Blood Viscosity and Obstruction on Microcirculation. Diabetes could arouse microangiopathy and often accompanied by the obstruction on microcirculation, which easily make the blood solidification and thrombosed. If there is thrombus in the microcirculation within kidney, the nephron would be hypoxic and ischemic, so the renal function decreases.
2. Hyperglycemia. Persistent hyperglycemia could develop into the hypertransfusion and hyper-filtration on glomerulus, thus make damage to ball mesangium, basement membrane and capillary endothelium, etc, which would make further impairment to glomerulus and kidney tubules. That factors triggering DN would eventually induce glomerulus atherosclerosis, thus cause the damage to nephron and arouse the renal dysfunction.
3. High Protein Diet. Protein-rich diet is also the factor that result DN. It would add burden to kidney and aggravate the proteinuria, which would form a vicious circle. So, daily intake for protein could no more than 40g.
4. Hyperlipaemia. Dyslipidemia is very common in the patients of diabetes. It can boost glomerulosclerosis and accelerate the progress of (Diabetic Nephropathy )DN.
5. Hypertension. Hypertension could make both the renal vascular resistance and the pressure inside kidney increased, and make the renal blood flow decreased, etc, which lead to proteinuria, glomerulosclerosis and renal failure. These are the factors for (Diabetic Nephropathy )DN.
6. Genetic Factor: Most diabetic patients would not have the kidney disease at last. However, some patients, who control the serum glucose very well for a long time, could also have an appearance of (Diabetic Nephropathy ) DN. Glucose transport protein-1(GLUT1) is the main transporter for glucose on glomerulus mesangial cells. This factor causing(Diabetic Nephropathy ) DN is more common.
7. Metabolic Disturbance
The clinical experimental researches indicate that, metabolic disturbance is the main factor that causes (Diabetic Nephropathy ) DN.
As a result of the continuous state of hyperglycemia resulted by lack of insulin, the disaccharide units that are formed by combining with galactose were increased, and meanwhile, along with the increase in the activity of glucose transfer on kidney, glycoprotein synthesis is increased and they deposit abundantly on basilemma. The hyperglycemia makes the HbA1c on glomerulus capillary basement membrane increased and influence the increase of connection permeability on polypeptide. As a result of the hypertrophy, proliferation and exudation of basilar membrane, microangiopathy is caused, which is also the common factor that result (Diabetic Nephropathy ) DN.
8. Endocrine Disorders
There is a close connection between secretion and the factors leading to (Diabetic Nephropathy )DN. Somatotropin could boost the protein synthesis and promote the synthesis and incrassation of basement membrane protein. Someone made a mouse involved in DN by injecting streptozocin(STZ) after cutting its hypophysis, and then gave it small doses somatotropin, the result is that its glomerulus basement membrane was significantly thickened, which illustrate that somatotropin is also one of the factors that lead to (Diabetic Nephropathy )DN.
The above are the explanations for (Diabetic Nephropathy )DN made by experts, we hope to help you. Here experts remind us, if anyone involve in any kind of disease, do not delay for a treatment, otherwise it would be very dangerous because some disease would worsen or trigger other disease and so on.
1. Increase on Blood Viscosity and Obstruction on Microcirculation. Diabetes could arouse microangiopathy and often accompanied by the obstruction on microcirculation, which easily make the blood solidification and thrombosed. If there is thrombus in the microcirculation within kidney, the nephron would be hypoxic and ischemic, so the renal function decreases.
2. Hyperglycemia. Persistent hyperglycemia could develop into the hypertransfusion and hyper-filtration on glomerulus, thus make damage to ball mesangium, basement membrane and capillary endothelium, etc, which would make further impairment to glomerulus and kidney tubules. That factors triggering DN would eventually induce glomerulus atherosclerosis, thus cause the damage to nephron and arouse the renal dysfunction.
3. High Protein Diet. Protein-rich diet is also the factor that result DN. It would add burden to kidney and aggravate the proteinuria, which would form a vicious circle. So, daily intake for protein could no more than 40g.
4. Hyperlipaemia. Dyslipidemia is very common in the patients of diabetes. It can boost glomerulosclerosis and accelerate the progress of (Diabetic Nephropathy )DN.
5. Hypertension. Hypertension could make both the renal vascular resistance and the pressure inside kidney increased, and make the renal blood flow decreased, etc, which lead to proteinuria, glomerulosclerosis and renal failure. These are the factors for (Diabetic Nephropathy )DN.
6. Genetic Factor: Most diabetic patients would not have the kidney disease at last. However, some patients, who control the serum glucose very well for a long time, could also have an appearance of (Diabetic Nephropathy ) DN. Glucose transport protein-1(GLUT1) is the main transporter for glucose on glomerulus mesangial cells. This factor causing(Diabetic Nephropathy ) DN is more common.
7. Metabolic Disturbance
The clinical experimental researches indicate that, metabolic disturbance is the main factor that causes (Diabetic Nephropathy ) DN.
As a result of the continuous state of hyperglycemia resulted by lack of insulin, the disaccharide units that are formed by combining with galactose were increased, and meanwhile, along with the increase in the activity of glucose transfer on kidney, glycoprotein synthesis is increased and they deposit abundantly on basilemma. The hyperglycemia makes the HbA1c on glomerulus capillary basement membrane increased and influence the increase of connection permeability on polypeptide. As a result of the hypertrophy, proliferation and exudation of basilar membrane, microangiopathy is caused, which is also the common factor that result (Diabetic Nephropathy ) DN.
8. Endocrine Disorders
There is a close connection between secretion and the factors leading to (Diabetic Nephropathy )DN. Somatotropin could boost the protein synthesis and promote the synthesis and incrassation of basement membrane protein. Someone made a mouse involved in DN by injecting streptozocin(STZ) after cutting its hypophysis, and then gave it small doses somatotropin, the result is that its glomerulus basement membrane was significantly thickened, which illustrate that somatotropin is also one of the factors that lead to (Diabetic Nephropathy )DN.
The above are the explanations for (Diabetic Nephropathy )DN made by experts, we hope to help you. Here experts remind us, if anyone involve in any kind of disease, do not delay for a treatment, otherwise it would be very dangerous because some disease would worsen or trigger other disease and so on.
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