Wednesday, June 12, 2013

What Are the Symptoms of Stage 5 Kidney Disease?

What are the symptoms of stage 5 kidney disease? Chronic kidney disease stage 5 means that patients have become uremia stage. GFR is less than 15 and serum creatinine is more than 707umol/L. In this stage, there are many toxins which accumulate in the body because kidney fails. The toxins give damage to many other organs or systems such as digestive system, nerve system, heart and so on.
As for digestive system’s damage, patients will feel nausea, vomiting, poor appetite, etc. As for the nerve system, patients may easy fall asleep, fatigue, dizzy, etc. Stage 5 kidney disease can also have anemia, which is caused by the insufficiency of EPO generation. EPO is produced in kidney. When kidney fails, the secretion decreases, the red blood cells can not generate normally, thus causing anemia and patients look pale on face. In turn, kidney failure leads to many toxins in the body, which threaten the life of red blood cells, worsening anemia.
What’s more, high blood pressure or hypertension will also take place in stage 5 of chronic kidney disease.
About 23% to 70% patients with chronic renal glomerular nephritis will suffer from high blood pressure with the disease developing. The more renal function declines, the higher blood pressure will be. In addition, lesion in renal parenchyma and renal tubules can also lead to high blood pressure such as insufficiency of chronic pyelonephritis. Half of them can lead to high blood pressure. High blood pressure or hypertension will in turn damage kidney. High blood pressure makes the heart work harder and, over time, can damage blood vessels throughout the body. If the blood vessels in the kidneys are damaged, they may stop removing wastes and extra fluid from the body. The extra fluid in the blood vessels may then raise blood pressure even more. It's a dangerous cycle.
Pain in the back can also takes place, especially for those with PKD, renal cysts and so on. Other kidney disease patients can also feel painful in back when it is knocked.

Stage 3 Chronic Kidney Disease Alternative Medicine Treatment

In the third stage of Chronic Kidney Disease, patients’ GFR (glomerular filtration rate) falls to 30~59ml/(min•1.73㎡). Patients fall into renal failure stage based on Chinese traditional standard. The serum creatinine rises to 442 to 707μmol/L(5~8mg/dl). The creatinine clearance rate declines to 20 to 10 ml/min. BUN ( blood urea nitrogen) increased to 179~286mmol/L(50~80mg/dl). Patients with CKD (Chronic Kidney Disease) Stage 3 can also have some symptoms. They will suffer from anemia, balance disorders of water, electrolyte and acid-base.
So stage 3 Chronic Kidney Disease patients are seeking for an effective treatment to get rid of suffering from it. How many alternative medicine treatments are there for patients with stage 3 CKD (Chronic Kidney Disease)? Generally, there are three chief methods.
One is western medicine, which mainly includes a variety of hormones and immunosuppressive agents, both of which have no effective methods. Why? They both can play roles in anticoagulation and inhibit immune. But they can only diminish the inflammatory reaction in a short time, control the symptoms for the time being and stop the intrinsic cells from being damaged again. Once patients with Chronic Kidney Disease are caught by cold, tiredness, etc, nephritis will recur again and become even worse. In addition, western medicine has side effects, which can even does harm to kidney.
The second one is Chinese medicine. How about Chinese medicine?
Here, before talking about Chinese medicine, it is necessary to say something about the pathological mechanism of kidney disease. According to the experts in Chinese medicine, the root of most kidney disease is the insufficiency of blood and oxygen in the kidney. When kidney is in the insufficiency of blood and oxygen, some intrinsic cells in the kidney will be damaged. With the long time lasting of insufficiency of blood and oxygen, some intrinsic cells even get necrotic, leading to renal fibrosis at last. In stage 3 of chronic kidney disease, lots of intrinsic cells are damaged and even get necrotic, leading to the shrink of kidney.
Aimed at repairing the damaged intrinsic cells, Chinese medicine contains many active and nutritious materials, which can improve the insufficiency of blood and oxygen, repair the damaged intrinsic cells and recover renal function. One shortcoming for Chinese medicine is that it has nothing to do with the necrotic cells. So, when kidney disease is serious, for example, stage 3 of chronic kidney disease, we should search another therapy.
The third therapy is stem cell transplant, which can make up or complement the shortcoming of Chinese medicine. Stem cells have potential to differentiate into cells which has different functions which the body or the kidney is in need of. So it can regenerate into necrotic intrinsic cells and revive the renal function.
In other words, the combination of Chinese medicine and stem cell can achieve a better treatment.

Can CKD Cause Back Pain

Can CKD cause back pain? Yes. CKD(Chronic Kidney Disease) can not only influence the renal function, but also leads to the chain reaction in many other part such as back. Back has close relationship with kidney. Many patients with CKD(Chronic Kidney Disease)has different degree of pain. And generally, pain which is caused by kidney disease can be divided into the following kinds.
The first kind is swelling kidney caused by renal parenchyma. It is usually caused by acute renal glomerular nephrtis, progressive nephritis, and so on. The swelled kidney stretches renal capsule, which can lead to continuous dull pain or distendingpain. Some of patients can also have gross hematuria, edema, high blood pressure and so on.
The second kind is infectious kidney disease. It is often seen in nephrapostasis, acute pyelonephritis, which is always due to infections of bacteria. Pain usually takes place in one side of the kidney, which will be more serious if pressed. In addition, infectious kidney disease can also be accompanied by fever, chill. It can be diagnosed by test of blood or urine.
The third kind of pain is caused by renal cyst. With the cysts growing in or outside of the kidney, their size will become bigger and bigger, which will press or squeeze the renal tissues or other normal cells which is located around the cyst. What’s more, some cysts inside the kidney can also grow to renal capsule, stretch kidney capsules, which leads to the continuous bursting pain or dull pain. Cysts in the kidney can be diagnosed by B ultrasound or CT.
The fourth kind of pain is caused by kidney stone. It can be intermittent, which spreads to the perineum. It is sometimes together with vomiting, nausea, and even gross hematuria when it is serious.
The last kind of pain is caused by Diabetic Nephropathy. Pain can be caused by nerve invasion. At the end stage of kidney disease, the adjustment function of kidney is damaged. So in clinic, continuous pain in back comes into being.
Back pain is a common symptom in CKD(chronic kidney disease) patients in clinic. If patients still have other symptoms such as hematuria, proteinuria, edema or high blood pressure, they should have an examination on urine or blood test to make a diagnosis whether patients are suffering from CKD. Once diagnosed with CKD, patients should receive treatment as soon as possible.

Sunday, June 9, 2013

Can I Live Long with CKD Stage 3?

Half a year ago, I was diagnosed with CKD stage 3. Then, I took treatment in local hospital. The medicine I use was such as prednisone, immunosuppressive agent and so on. The treatment at that time was successful. My serum creatinine decreased from 300 to 235umol/L. I could not feel any discomfort. However, recently, after a flu and fatigue from work, I had protein in urine, which makes me scared. I am concerned whether chronic kidney disease can be treated well and how long can I live?
Dear sir, firstly, please do not worry. From what you describe, after the treatment, kidney disease recurs, which leads to your anxiety. What I want to say first is that as long as we receive proper treatment, kidney disease will not recur.
Secondly, I would like to recommend you an effective therapy: immunotherapy in our Hospital. As we mentioned in the previous articles, most kidney diseases are caused by immune problem. Immunotherapy can adjust the immune system and help chronic kidney disease stage 3 patients recover fundamentally. In stage 3, the GFR decreased obviously, and there has been more immune complex deposition on the kidney for the excessive immune reaction has happened about at least several months ago.
In this case, firstly, before immune adjustment, we should have an immune diagnosis, in which case, we can figure out where exactly the immune complex deposits and the accurate amount of it, which supplies valuable evidence for the treatment of the doctors. Next, chronic kidney disease patients stage 3 will receive immune clearance, which can help clear away the immune complex in the blood and create a good treatment environment for the immunotherapy.
When stage 3 chronic kidney disease patients come to immune adjustment stage, many Chinese medicine and western medicine are applied such as Chinese Medicine and stem cell therapy. It is more advanced that the immune therapy in western medicine for it can repair the damaged intrinsic cells, differentiate into those which have been necrotic, rebuild renal function and increase the immune ability, thus treating stage 3 chronic kidney disease fundamentally.

CKD Stage 2 Is the Best Time for the Treatment

According to GFR, chronic kidney disease can be divided into 5 stages. In stage2, GFR(glomerular filtration rate)declines to 60-89 ml/min. The normal range is 80 to 120 ml/min. Younger men has higher GFR than old people. Serum creatinine is 133-177umol/L. The normal range is 44 to 103 umol/L.
In the early stage of chronic kidney disease especially stage 1 and stage 2, there is nearly no symptom in clinic for kidney has a strong compensation ability. In China, some people think kidney is dumb. People usually do not pay attention to it. However, once serum creatinine rises, it indicates that the damage in the kidney is more than half. If we do not treat it timely, kidney will become atrophic for there are damaged intrinsic cells in the kidney. Of course, the earlier, the better.
Here, we’d like to introduce several methods to help discover chronic kidney disease early.
1. Test urine twice a year. If there is something wrong in the kidney, serum creatinine, urea acid will rise. Blood or protein will appear in urine when the renal glomerular membrane is damaged.
2. People with PKD, high blood pressure, diabetes or whose parents have such diseases should beware for they are hereditary.
3. In stage 2 of chronic kidney disease, people may have a little pain in back, feel fatigue and increased urine at night.
If we have found that we have come into stage 2, we should treat it timely and effectively. In our Hospital, we have immunotherapy for most kidney diseases are caused by immune problem. Immunotherapy can be divided into 6 steps such as immune diagnosis, immune clearance, immune inhibition, immune tolerance, immune adjustment and immune protection. In this passage, we mainly introduce the immune adjustment and immune protection, which are the core treatment in our kidney disease hospital.
After immune diagnose and immune clearance, we can exactly know the type of kidney disease, the amount of the immune complex and the area of immune complex and clear away the toxins in the blood, including immune complex.
Then, Chinese Medicine is applied. Chinese Medicine is a natural herbal therapy applied externally on acupoint of lower back. Herbal bags containing dozens of herbal medicines are soaked previously in penetrants, and then placed on the lower back part. With the help of osmosis device, effective ingredients of herbal medicines will infiltrate into kidneys through the main channels. After the application of Chinese Medicine, people with kidney failure may sweat in the center of palm and feet, which indicates that the micro-circulation is improved.In detail, it can repair the damaged intrinsic cells after it is into the body for it contains natural herbs and active substances.
At last, stem cell is applied if there are too many damaged cells and even some necrotic cell in stage 2 chronic kidney disease for stem cell can not only repair but also differentiate. Stem cell is especially good for diseases such as lupus nephritis, purpura nephritis,etc.

Management of chronic kidney disease stage 2

Stage 2 chronic kidney disease is easy to recover for kidney is still in compensation stage. As long as we take effective treatment measures and have a good management to assist the treatment, the effect will be good. How to manage? It goes as follows:
1. Do blood test and urine test to monitor the protein in urine, serum creatinine level, etc. In addition, ECT test is also necessary which can tell us the GFR, which reflects how kidney functions and is short for glomerular filtration rate.
2. Keep a healthy diet is also necessary.
§ Limit intake of refined and processed foods high in sugar and sodium
§ Choose and prepare foods with less salt or high sodium ingredients
§ Keep protein intake within the Daily Reference Intake (DRI) level recommended for healthy people
§ Consum the DRI for vitamins and minerals
§ Potassium and phosphorus are usually not restricted unless blood levels are above normal
3. Keep stage 2 chronic kidney disease patients’ blood pressure at a healthy level
a) 125/75 for those with diabetes
b) 130/85 for non-diabetes and non-proteinuria
c) 125/75 for non-diabetes with proteinuria
4. Stop drinking alcohol and smoking. Long time drinking wine or alcohol can lead to anemia, and the disorder of blood cells. Kinds of bleeding are due to the bad absorption of stomach and guts, which also lead to low use ratio of vitamin. In addition, the increased discharge of vitamin can lead to hyperlipidaemia.
5. Stop coffee. Long time drinking coffee can make patients with stage 2 kidney disease have kidney stone, which can increase the burden of the kidney. The elements in coffee can increase the amount of calcium in the urine, which is the main reason why patients have kidney stone.

Friday, June 7, 2013

What is Renal Insufficiency

Renal Insufficiency is caused by many reasons. The renal glomeruli are damaged seriously, which leads to the disorder of electrolyte, acid-base balance. Renal insufficiency can be divided into acute renal insufficiency and chronic renal insufficiency. The prognosis is not good and threatens people’ s life.
The pathogenesis of renal insufficiency
Firstly, renal insufficiency can be caused by kidney disease such as acute kidney failure, chronic kidney failure, pyelonephritis, nephrotuberculosis, renal tubules degeneration caused by chemical toxicant and biological poisons, etc.
Secondly, renal insufficiency can also be caused by barrier in the whole blood circulation such as shock, heart failure, high blood pressure, etc.
Renal insufficiency can be divided into 4 stages.
The third stage is called compensation stage. Because kidney has a strong ability of compensation,symptoms will not occur. Even though some renal glomeruli are damaged, other remained renal glomeruli can still work and do more work to take place those which are damaged. The ability of secretion and electrolyte balance can also meet the need. So in clinic, there is no symptom. In renal function test, we can find out that some index can be in normal range and can be a little high.
In the second stage, we call it renal insufficiency stage. Many glomeruli are damaged in this stage, which account for 60% to 75%. Kidney has difficulties in discharging metabolism. Serum creatinine and BUN (blood urea nitrogen) will become slightly high. Patients can suffer from anemia, fatigue, decreased body weight, and can not concentrate well. All of them can be ignored easily. However, if patients loose water in the body, or suffer from infection, bleeding, etc, their symptoms will appear obviously.
In the third stage, it is called renal failure stage. The damage in the kidney has become rather serious, accounting for 75% to 95%. The inner environment can not maintain stable. In addition, patients will get tired easily and will feel fatigue, and can not concentrate, etc. Anemia is not serious as well. Urine at night becomes more. What’s more, serum creatinine increases. BUN increases as well. Patients can also be accompanied by acidosis. So this stage can also be called azotemia.
In the fourth stage, patients with renal insufficiency develop into advanced stage kidney disease or uremia stage. In this stage, damage of renal glomeruli spreads to 95%. Patients have serious clinical symptoms such as nausea, vomiting, little urine, edema, high blood pressure, serious edema and anemia, itch in skin, and so on.